Literature DB >> 26715953

A review of patients with advanced cervical cancer presenting to palliative care services at Queen Elizabeth Central Hospital in Blantyre, Malawi.

M J Bates1, A Mijoya1.   

Abstract

BACKGROUND: Cervical cancer is the commonest cancer affecting women in Malawi, which has the highest rate of this disease in the world. Most cases are diagnosed at an advanced stage. AIM: To describe the symptom burden, palliative care interventions, and outcomes of cervical cancer patients who entered care at Tiyanjane Clinic in Blantyre, Malawi, between January and December 2012.
METHODS: We reviewed the case files of 72 patients presenting to our hospital-based palliative care service over one year.
RESULTS: The mean age was 49.5 years. Twenty-six patients (36%) were HIV-positive and the majority of these (n = 22; 85%) were on antiretroviral medication at presentation to palliative care. Pain (n = 66; 92%), vaginal discharge (n = 44; 61%), and unpleasant odour (n = 37; 51%) were commonly reported. Over a third of patients (n = 26; 36%) reported pain in two or more sites. Fourteen patients (19%) reported vaginal bleeding. Spousal breakdown (through widowhood or divorce) was noted in over half (n = 41; 57%) of all cases. Pain relief was provided to 69 (96%) of the patients (morphine to 40 patients; 56%). Common interventions provided included metronidazole tablets (used vaginally), sanitary items, and counselling. At the end of the study period, 18 patients (25%) were still under the care of palliative services.
CONCLUSIONS: Access to medications such as morphine, metronidazole and tranexamic acid can improve quality of life, even when radiotherapy is limited. Health care teams require necessary skills and training, including how to perform a comprehensive assessment, with an emphasis on the provision of psychosexual counselling, to assist with the complexity of symptoms occurring in this vulnerable group.

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Year:  2015        PMID: 26715953      PMCID: PMC4688869          DOI: 10.4314/mmj.v27i3.4

Source DB:  PubMed          Journal:  Malawi Med J        ISSN: 1995-7262            Impact factor:   0.875


  8 in total

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Journal:  Eur J Cancer       Date:  2010-09-06       Impact factor: 9.162

2.  Audit of gynaecological cancers Queen Elizabeth Central Hospital, Blantyre.

Authors:  Frank Taulo; Eddie Malunga; Andrew Ngwira
Journal:  Malawi Med J       Date:  2008-12       Impact factor: 0.875

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4.  Hospital based palliative care in sub-Saharan Africa; a six month review from Malawi.

Authors:  Julia B Tapsfield; M Jane Bates
Journal:  BMC Palliat Care       Date:  2011-07-09       Impact factor: 3.234

5.  Health systems challenges in cervical cancer prevention program in Malawi.

Authors:  Fresier C Maseko; Maureen L Chirwa; Adamson S Muula
Journal:  Glob Health Action       Date:  2015-01-22       Impact factor: 2.640

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Authors:  Michael E Herce; Shekinah N Elmore; Noel Kalanga; James W Keck; Emily B Wroe; Atupere Phiri; Alishya Mayfield; Felix Chingoli; Jason A Beste; Listern Tengatenga; Junior Bazile; Eric L Krakauer; Jonas Rigodon
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7.  Population-level effect of HIV on adult mortality and early evidence of reversal after introduction of antiretroviral therapy in Malawi.

Authors:  Andreas Jahn; Sian Floyd; Amelia C Crampin; Frank Mwaungulu; Hazzie Mvula; Fipson Munthali; Nuala McGrath; Johnbosco Mwafilaso; Venance Mwinuka; Bernard Mangongo; Paul E M Fine; Basia Zaba; Judith R Glynn
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8.  A six-year study of the clinical presentation of cervical cancer and the management challenges encountered at a state teaching hospital in southeast Nigeria.

Authors:  Justus N Eze; Esther N Emeka-Irem; Felix O Edegbe
Journal:  Clin Med Insights Oncol       Date:  2013-06-27
  8 in total
  12 in total

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3.  Cervical cancer in southern Malawi: A prospective analysis of presentation, management, and outcomes.

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4.  Cervical cancer screening - The challenges of complete pathways of care in low-income countries: Focus on Malawi.

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5.  Household concepts of wellbeing and the contribution of palliative care in the context of advanced cancer: A Photovoice study from Blantyre, Malawi.

Authors:  M Jane Bates; Treza Mphwatiwa; Jane Ardrey; Nicola Desmond; Louis W Niessen; S Bertel Squire
Journal:  PLoS One       Date:  2018-08-22       Impact factor: 3.240

6.  Regular Low-Dose Oral Metronidazole Is Associated With Fewer Vesicovaginal and Rectovaginal Fistulae in Recurrent Cervical Cancer: Results From a 10-Year Retrospective Cohort.

Authors:  Reena George; Thotampuri Shanthi Prasoona; Ramu Kandasamy; Thenmozhi Mani; Shakila Murali; Roja Rekha; Jayaprakash Muliyil
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7.  Palliative care needs among patients with advanced illnesses in Bhutan.

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8.  Age-specific burden of cervical cancer associated with HIV: A global analysis with a focus on sub-Saharan Africa.

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9.  Cancer Pathology Turnaround Time at Queen Elizabeth Central Hospital, the Largest Referral Center in Malawi for Oncology Patients.

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10.  Learning Curve, Survival Curve.

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