Literature DB >> 26715923

Bone marrow aspiration in north Sudan: the procedure, indications and the diagnostic value.

Wadie M Elmadhoun1, Sufian K Noor2, Sarra O Bushara2, Ahmed O Almobarak3, Nazik Elmalaika Husain4, Mohamed H Ahmed5.   

Abstract

INTRODUCTION: Bone marrow aspiration (BMA) is a common and useful investigation tool in clinical practice to obtain information about both hematological and non-hematological disorders. The aim of the work was to identify the main indications for BMA in Atbara city, north Sudan and to determine the common diagnoses encountered.
METHODS: All reports of BMA carried out during a 6-year period from 2009 to 2014, in the Modern Specialized Laboratory (the only site where BMA is conducted in Atbara) were reviewed. The information extracted included the main indications for performing this procedure, age groups involved, and the most common diagnoses established. A specially designed form was used for this purpose and the data were analyzed using SPSS computer program.
RESULTS: A total number of 112 cases were subjected to bone marrow aspiration. The most frequent indications were: pancytopenia 43(38.4%), anemia 39 (34.8%), and suspected leukemia 13 (11.6%). In 86(76.8%) cases, BMA provided either the diagnosis or diagnostic clues to the disease process, while 26 (23.2%) of the aspirates revealed a normally functioning marrow.
CONCLUSION: Bone marrow aspiration is an important investigation for establishing the diagnosis in many medical conditions. The most common indication for this procedure in our study was pancytopenia and the most common finding was aplastic anemia.

Entities:  

Keywords:  Atbara; Bone marrow aspiration; Sudan

Year:  2015        PMID: 26715923      PMCID: PMC4682598     

Source DB:  PubMed          Journal:  Int J Health Sci (Qassim)        ISSN: 1658-3639


  10 in total

Review 1.  Bone marrow aspiration and biopsy: collection and interpretation.

Authors:  K G Trewhitt
Journal:  Oncol Nurs Forum       Date:  2001-10       Impact factor: 2.172

Review 2.  Bone marrow aspiration.

Authors:  B J Bain
Journal:  J Clin Pathol       Date:  2001-09       Impact factor: 3.411

3.  Bone marrow trephine biopsy as an adjunct to bone marrow aspiration.

Authors:  Annu Nanda; Sabita Basu; Neelam Marwaha
Journal:  J Assoc Physicians India       Date:  2002-07

Review 4.  Modern techniques for the diagnostic evaluation of the trephine bone marrow biopsy: methodological aspects and applications.

Authors:  Falko Fend; Alexandar Tzankov; Karin Bink; Stefan Seidl; Leticia Quintanilla-Martinez; Marcus Kremer; Stephan Dirnhofer
Journal:  Prog Histochem Cytochem       Date:  2008-01-04

5.  Videos in clinical medicine. Bone marrow aspiration and biopsy.

Authors:  Suman Malempati; Sarita Joshi; Susanna Lai; Dana A V Braner; Ken Tegtmeyer
Journal:  N Engl J Med       Date:  2009-10-08       Impact factor: 91.245

Review 6.  Making the most of bone marrow trephine biopsy.

Authors:  Bridget S Wilkins; David M Clark
Journal:  Histopathology       Date:  2009-12       Impact factor: 5.087

Review 7.  Pitfalls in bone marrow pathology: avoiding errors in bone marrow trephine biopsy diagnosis.

Authors:  Bridget S Wilkins
Journal:  J Clin Pathol       Date:  2011-02-15       Impact factor: 3.411

8.  Bone marrow aspiration technique has deteriorated in recent years.

Authors:  M Remberger; O Ringdén; J Mattsson
Journal:  Bone Marrow Transplant       Date:  2015-04-20       Impact factor: 5.483

9.  Bone marrow examination. Indications and diagnostic value.

Authors:  Layla A Bashawri
Journal:  Saudi Med J       Date:  2002-02       Impact factor: 1.484

10.  Hematological profile in pyrexia of unknown origin: role of bone marrow trephine biopsy vis-à-vis aspiration.

Authors:  Ruchika Gupta; Namrata Setia; Prerna Arora; Sompal Singh; Tejinder Singh
Journal:  Hematology       Date:  2008-10       Impact factor: 2.269

  10 in total

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