Literature DB >> 26715423

Hepatitis B and C Virus Infection and Risk of Pancreatic Cancer: A Population-Based Cohort Study (JPHC Study Cohort II).

Sarah Krull Abe1, Manami Inoue2, Norie Sawada3, Motoki Iwasaki3, Taichi Shimazu3, Taiki Yamaji3, Shizuka Sasazuki3, Eiko Saito4, Yasuhito Tanaka5, Masashi Mizokami6, Shoichiro Tsugane3.   

Abstract

BACKGROUND: The aim of this study was to assess the association between hepatitis B virus (HBV) and hepatitis C virus (HCV) and the risk of pancreatic cancer among Japanese adults.
METHODS: A total of 20,360 subjects of the Japan Public Health Center (JPHC)-based prospective study cohort II with available data on HBV and HCV infection status from blood samples were followed up until the end of 2010 for an average of 16 years. Cox proportional hazards models were employed to calculate HRs and 95% confidence intervals (CI).
RESULTS: During 324,394 person-years, 116 newly diagnosed cases of pancreatic cancer were identified. Compared with individuals without a positive infection marker, the multivariate-adjusted HRs were 1.22 (95% CI, 0.81-1.84) for anti-HBc and 0.69 (95% CI, 0.28-1.69) for anti-HCV. There were no pancreatic cancer cases among HBsAg-positive participants.
CONCLUSION: In the JPHC study, we did not observe a statistically significant association between hepatitis B or C and the risk of pancreatic cancer. IMPACT: Our results do not support an association between hepatitis B or C and the risk of pancreatic cancer. ©2015 American Association for Cancer Research.

Entities:  

Mesh：

Year:  2015        PMID： 26715423     DOI： 10.1158/1055-9965.EPI-15-1115

Source DB:  PubMed          Journal:  Cancer Epidemiol Biomarkers Prev        ISSN： 1055-9965            Impact factor:   4.254


  10 in total

1.  Helicobacter pylori infection, atrophic gastritis, and risk of pancreatic cancer: A population-based cohort study in a large Japanese population: the JPHC Study.

Authors:  Mayo Hirabayashi; Manami Inoue; Norie Sawada; Eiko Saito; Sarah K Abe; Akihisa Hidaka; Motoki Iwasaki; Taiki Yamaji; Taichi Shimazu; Shoichiro Tsugane
Journal:  Sci Rep       Date:  2019-04-15       Impact factor: 4.379

Review 2.  Extrahepatic cancers and chronic HCV infection.

Authors:  Stanislas Pol; Anaïs Vallet-Pichard; Olivier Hermine
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2018-01-17       Impact factor: 46.802

3.  Higher Levels of Fibrosis in a Cohort of Veterans with Chronic Viral Hepatitis are Associated with Extrahepatic Cancers.

Authors:  Ameer Abutaleb; Jose Antonio Almario; Saleh Alghsoon; Ji Ae Yoon; Kate Gheysens; Shyam Kottilil; Eleanor Wilson
Journal:  J Clin Exp Hepatol       Date:  2020-08-09

4.  Cancer in People with and without Hepatitis C Virus Infection: Comparison of Risk Before and After Introduction of Direct-Acting Antivirals.

Authors:  Julia L Marcus; Michael J Silverberg; Jennifer O Lam; Leo B Hurley; Jennifer B Lai; Varun Saxena; Suk Seo; Scott Chamberland; Charles P Quesenberry; Jamila H Champsi; Joanna Ready; Elizabeth Y Chiao
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2021-09-28       Impact factor: 4.090

Review 5.  Hepatitis C Virus and Nonliver Solid Cancers: Is There an Association between HCV and Cancers of the Pancreas, Thyroid, Kidney, Oral Cavity, Breast, Lung, and Gastrointestinal Tract?

Authors:  Saad Qadwai; Tayyaba Rehman; Jonathan Barsa; Zeeshan Solangi; Edward Lebovics
Journal:  Gastroenterol Res Pract       Date:  2017-05-03       Impact factor: 2.260

Review 6.  Environmental Risk Factors of Pancreatic Cancer.

Authors:  Hui-Jen Tsai; Jeffrey S Chang
Journal:  J Clin Med       Date:  2019-09-10       Impact factor: 4.241

7.  Elevated risk of colorectal, liver, and pancreatic cancers among HCV, HBV and/or HIV (co)infected individuals in a population based cohort in Canada.

Authors:  Maryam Darvishian; Zahid A Butt; Stanley Wong; Eric M Yoshida; Jaskaran Khinda; Michael Otterstatter; Amanda Yu; Mawuena Binka; Carmine Rossi; Geoff McKee; Margo Pearce; Maria Alvarez; Jason Wong; Darrel Cook; Troy Grennan; Jane Buxton; Mark Tyndall; Ryan Woods; Mel Krajden; Parveen Bhatti; Naveed Z Janjua
Journal:  Ther Adv Med Oncol       Date:  2021-02-11       Impact factor: 8.168

8.  Associations between hepatitis B virus exposure and the risk of extrahepatic digestive system cancers: A hospital-based, case-control study (SIGES).

Authors:  Hui Wang; Xin-Zu Chen; Xiao-Long Chen; Wei-Han Zhang; Kai Liu; You-Juan Wang; Huai-Rong Tang; Jian-Kun Hu
Journal:  Cancer Med       Date:  2021-05-02       Impact factor: 4.452

9.  Prognostic impact of hepatitis B virus infection in patients with primary cervical cancer.

Authors:  Xiaoyan Feng; Huaiwu Lu; Yuan Wei; Meimei Guan; Junyi Wang; Changhao Liu; Tianran Shen; Qingsong Chen; Qunxian Rao
Journal:  Cancer Med       Date:  2021-10-21       Impact factor: 4.452

10.  Kashmiri refugees at the verge of hepatitis B and C epidemic in the State of Azad Jammu and Kashmir, Pakistan.

Authors:  Syed Ayaz Kazmi; Abdul Rauf; Farheen Shafique; Noreen Asim; Nuzhat Shafi; Mahreen Ul Hassan
Journal:  Rev Saude Publica       Date:  2022-05-06       Impact factor: 2.772
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.