Literature DB >> 26714143

The role of endoscopic bladder tumour assessment in the management of patients subjected to transurethral bladder tumour resection.

M A Skrzypczyk1, Ł Nyk2, P Szostek2, S Szempliński1, A Borówka2, J Dobruch1,2.   

Abstract

Despite complete resection, non-muscle invasive bladder cancers tend to recur. Therefore, their risk stratification was implemented to select adjuvant therapy. Immediate intravesical chemotherapeutic instillations were shown to decrease the risk of recurrence in those with low-risk disease. The purpose of the study was to determine the role of endoscopic assessment in the management of patients subjected to transurethral resection of the bladder tumour (TURBT). In 262 patients submitted to TURBT due to primary bladder tumour, the size and the number of the lesion(s) were noted and the stage as well as the grade of the tumour(s) were typed. The individual features were then scored according to the European Organisation of Research and Treatment of Cancer 'Bladder Calculator' and the lesions were classified into the low, intermediate and high risk of recurrence group. Clinical evaluation was then compared with pathological report and final triage. Based on the clinical data, 95 (36.25%), 105 (40.07%) and 3 (1.14%) patients were endoscopically assigned to the groups of low, intermediate and high risk of recurrence respectively. After pathological report, correct risk stratification was confirmed in 86 (90.5%), 95 (90.5%) and 3 (100%) patients respectively. Endoscopic assessment of bladder cancers allows to accurately establish the risk of recurrence and may facilitate implementation of adjuvant therapy before histological evaluation.
© 2015 John Wiley & Sons Ltd.

Entities:  

Keywords:  bladder cancer; risk stratification; transurethral resection

Mesh:

Year:  2015        PMID: 26714143     DOI: 10.1111/ecc.12431

Source DB:  PubMed          Journal:  Eur J Cancer Care (Engl)        ISSN: 0961-5423            Impact factor:   2.520


  3 in total

1.  Endoscopic appearance of a tumor can predict the stage of bladder cancer.

Authors:  Sławomir Poletajew; Piotr Radziszewski
Journal:  Cent European J Urol       Date:  2017-03-14

Review 2.  TGF-β and microRNA Interplay in Genitourinary Cancers.

Authors:  Joanna Boguslawska; Piotr Kryst; Slawomir Poletajew; Agnieszka Piekielko-Witkowska
Journal:  Cells       Date:  2019-12-12       Impact factor: 6.600

3.  Preoperative pyuria predicts the presence of high-grade bladder carcinoma in patients with bladder tumors.

Authors:  Sławomir Poletajew; Dominika Gajewska; Krystian Kaczmarek; Wojciech Krajewski; Marcin Łykowski; Joanna Sondka-Migdalska; Michał Borowik; Paweł Buraczyński; Mateusz Dzięgała; Maciej Przudzik; Marcin Słojewski; Piotr Kryst
Journal:  Cent European J Urol       Date:  2020-12-03
  3 in total

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