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Literature DB >> 26713369

Neosartoryadins A and B, Fumiquinazoline Alkaloids from a Mangrove-Derived Fungus Neosartorya udagawae HDN13-313.

Guihong Yu¹, Guoliang Zhou¹, Meilin Zhu¹, Wei Wang¹, Tianjiao Zhu¹, Qianqun Gu¹, Dehai Li¹.

Abstract

Neosartoryadins A (1) and B (2), both with a unique 6/6/6/5 quinazoline ring system connected directly to a 6/5/5 imidazoindolone ring, together with three biogenetically related compounds 3-5, were isolated from the endophytic fungus Neosartorya udagawae HDN13-313. The absolute configurations of new compounds 1-4 were established. Compounds 1 and 2 displayed anti-influenza virus A (H1N1) activities with IC50 values of 66 and 58 μM, respectively (ribavirin as positive control, IC50 = 94 μM).

Entities: Chemical Species

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Year: 2015 PMID： 26713369 DOI： 10.1021/acs.orglett.5b02964

Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005

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Cited

21 in total

Review 1. Biologically active quinoline and quinazoline alkaloids part II.

Authors: Xiao-Fei Shang; Susan L Morris-Natschke; Guan-Zhou Yang; Ying-Qian Liu; Xiao Guo; Xiao-Shan Xu; Masuo Goto; Jun-Cai Li; Ji-Yu Zhang; Kuo-Hsiung Lee
Journal: Med Res Rev Date: 2018-02-27 Impact factor: 12.944

2. Hexafluoroisopropanol mediated benign synthesis of 2H-pyrido[1,2-a]pyrimidin-2-ones by using a domino protocol.

Authors: Zakeyah Alsharif; Mohamad Akbar Ali; Hessa Alkhattabi; Derika Jones; Evan Delancey; P C Ravikumar; Mohammad A Alam
Journal: New J Chem Date: 2017-10-20 Impact factor: 3.591

3. Classification of Aspergillus, Penicillium, Talaromyces and related genera (Eurotiales): An overview of families, genera, subgenera, sections, series and species.

Authors: J Houbraken; S Kocsubé; C M Visagie; N Yilmaz; X-C Wang; M Meijer; B Kraak; V Hubka; K Bensch; R A Samson; J C Frisvad
Journal: Stud Mycol Date: 2020-06-27 Impact factor: 16.097

Neosartoryadins A and B, Fumiquinazoline Alkaloids from a Mangrove-Derived Fungus Neosartorya udagawae HDN13-313.

Review 1. Biologically active quinoline and quinazoline alkaloids part II.

2. Hexafluoroisopropanol mediated benign synthesis of 2H-pyrido[1,2-a]pyrimidin-2-ones by using a domino protocol.

3. Classification of Aspergillus, Penicillium, Talaromyces and related genera (Eurotiales): An overview of families, genera, subgenera, sections, series and species.

4. Hexafluoroisopropyl alcohol mediated synthesis of 2,3-dihydro-4H-pyrido[1,2-a]pyrimidin-4-ones.

5. Lipid-Lowering Polyketides from the Fungus Penicillium Steckii HDN13-279.

Review 6. Natural Products Research in China From 2015 to 2016.

Review 7. Potential of small-molecule fungal metabolites in antiviral chemotherapy.

Review 8. Structural Diversity and Biological Activities of Novel Secondary Metabolites from Endophytes.

9. Bioactive Chaetoglobosins from the Mangrove Endophytic Fungus Penicillium chrysogenum.

10. Secondary Metabolites from the Marine-Derived Fungus Dichotomomyces sp. L-8 and Their Cytotoxic Activity.