Sora Yasri1, Viroj Wiwanitkit2. 1. KMT Primary Care Center, Bangkok, Thailand. 2. KMT Primary Care Center, Bangkok, Thailand ; Visiting Professor, Hainan Medical University, China ; Visiting Professor, Faculty of Medicine, University of Nis, Serbia ; Adjunct Professor, Joseph Ayobabalola University, Nigeria ; Honorary Professor, Dr. DY Patil Medical University, Pune, Maharashtra, India.
Sir,The recent report on “Dot sign and dengue encephalitis” is very interesting.[1] The finding of dot sign in diagnosis of dengue encephalitis should be commented. In this case, “transient splenial hyperintensityappearing asdot sign in magnetic resonance imaging (MRI)” is mentioned.[1] Indeed, “dot sign” is classically mentioned in some diseases, but not infectious disease as dengue.[2] Transient splenial hyperintensitycan be seen in many neurological problems such as cryptococcal meningitis[3] and epilepsy.[4] The concomitant disorder in the present case is questionable. Indeed, dengue encephalitis is an uncommon neurological presentation of dengue and the clinical features can hardly be differentiated from other encephalitis.[5] The MRI seems to be not helpful for definitive and differential diagnosis.[5]