| Literature DB >> 26711237 |
Abstract
Notch signalling plays pivotal roles in development and homeostasis of all metazoan species. Notch is a receptor molecule that directly translates information of cell-cell contact to gene expression in the nucleus. Mastermind is a conserved and essential nuclear factor that supports the activity of Notch. Here, the past and current studies of the interplay between these factors are reviewed.Keywords: MAML; Mastermind; Notch signalling; signal transduction; transcription
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Year: 2015 PMID: 26711237 DOI: 10.1093/jb/mvv123
Source DB: PubMed Journal: J Biochem ISSN: 0021-924X Impact factor: 3.387