Jung Hwoon Edward Yoon1, Vadim Grechushkin1, Ammar Chaudhry1, Priya Bhattacharji1, Brian Durkin2, William Moore3. 1. Department of Radiology, State University of New York at Stony Brook, University Hospital, HSC Level IV, Room 060, Stony Brook, NY 11794. 2. Department of Anesthesiology, State University of New York at Stony Brook, University Hospital, HSC Level IV, Room 060, Stony Brook, NY 11794. 3. Department of Radiology, State University of New York at Stony Brook, University Hospital, HSC Level IV, Room 060, Stony Brook, NY 11794. Electronic address: william.moore@stonybrook.edu.
Abstract
PURPOSE: To evaluate the safety and efficacy of cryoneurolysis in patients with refractory peripheral neuropathic pain. MATERIALS AND METHODS: Twenty-two patients referred for cryoneurolysis of refractory peripheral neuropathy were recruited prospectively from July 2011 to July 2013. The mean patient age was 49.5 years, and 41% of patients were female. Ultrasound imaging of the involved nerves was used for guidance. Percutaneous ablations were performed with a PerCryo 17R device. Pain levels were recorded on a visual analog scale (scores 0-10) before and at 1, 3, 6, 9, and 12 months after the procedure, and complications were documented. RESULTS: Mean pain levels were 8.3 ± 1.9 before intervention and 2.3 ± 2.5 at 1 month, 3.2 ± 2.5 at 3 months, 4.7 ± 2.7 at 6 months, and 5.1 ± 3.7 at 12 months afterward. A Wilcoxon rank-sum test was performed and showed a statically significant decrease between pre- and postprocedural pain scores. There were no complications from the procedures. DISCUSSION: Cryoneurolysis caused a significant decrease in self-reported pain scores in patients with chronic refractory neuropathic pain, with moderately long-term relief. Cryoneurolysis is an additional therapy that can alleviate severe chronic neuropathic pain.
PURPOSE: To evaluate the safety and efficacy of cryoneurolysis in patients with refractory peripheral neuropathic pain. MATERIALS AND METHODS: Twenty-two patients referred for cryoneurolysis of refractory peripheral neuropathy were recruited prospectively from July 2011 to July 2013. The mean patient age was 49.5 years, and 41% of patients were female. Ultrasound imaging of the involved nerves was used for guidance. Percutaneous ablations were performed with a PerCryo 17R device. Pain levels were recorded on a visual analog scale (scores 0-10) before and at 1, 3, 6, 9, and 12 months after the procedure, and complications were documented. RESULTS: Mean pain levels were 8.3 ± 1.9 before intervention and 2.3 ± 2.5 at 1 month, 3.2 ± 2.5 at 3 months, 4.7 ± 2.7 at 6 months, and 5.1 ± 3.7 at 12 months afterward. A Wilcoxon rank-sum test was performed and showed a statically significant decrease between pre- and postprocedural pain scores. There were no complications from the procedures. DISCUSSION: Cryoneurolysis caused a significant decrease in self-reported pain scores in patients with chronic refractory neuropathic pain, with moderately long-term relief. Cryoneurolysis is an additional therapy that can alleviate severe chronic neuropathic pain.
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