Gui-Hua Yao1, Mei Zhang1, Li-Xue Yin2, Cheng Zhang1, Ming-Jun Xu1, Yan Deng2, Yan Liu1, You-Bin Deng3, Wei-Dong Ren4, Zhi-An Li5, Hong Tang6, Quan-Bin Zhang7, Yu-Ming Mu8, Li-Gang Fang9, Yun Zhang10. 1. Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Department of Cardiology, Qilu Hospital of Shandong University, 107 Wenhuaxi Road, Jinan 250012, China. 2. Department of Cardiovascular Ultrasound and Non-invasive Cardiology, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, 2nd West Section, 1st Roundway, Chengdu 610072, Sichuan, China. 3. Department of Medical Ultrasound, Tong Ji Hospital, Tong Ji Medical College, Hua Zhong University of Science and Technology, Wuhan, Hubei, China. 4. Department of Ultrasound, Affiliated Sheng Jing Hospital of China Medical University, Shenyang, Liaoning, China. 5. Department of Echocardiography, Beijing An Zhen Hospital of Capital Medical University, Beijing, China. 6. Department of Cardiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China. 7. Department of Ultrasound, The General Hospital of Taigang Affiliated to Shanxi Medical University, Taiyuan, Shanxi, China. 8. Department of Echocardiography, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China. 9. Department of Cardiology, Peking Union Medical College Hospital, Beijing, China. 10. Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Department of Cardiology, Qilu Hospital of Shandong University, 107 Wenhuaxi Road, Jinan 250012, China zhangyun@sdu.edu.cn.
Abstract
AIMS: Currently, available Doppler echocardiographic reference values are derived mainly from North American and European population studies, which may not applicable to the Chinese population. We aimed to establish normal reference values of Doppler echocardiographic parameters in a nationwide, population-based cohort of healthy Han Chinese adults. METHODS AND RESULTS: A total of 1394 qualified healthy subjects (mean age 47.3 ± 16.0 years, 678 men) were enrolled at 43 collaborating laboratories, 37 transvalvular flow and tissue Doppler parameters were obtained, and the impacts of gender and age on each parameter were analysed. Significant differences were found between men and women in 48.6% (18/37) of the parameters analysed, and among different age groups in 83.8% (31/37) of the parameters in men and in 86.5% (32/37) of the parameters in women. CONCLUSIONS: Normal reference values of Doppler echocardiographic parameters were established for the first time in a nationwide, population-based cohort of healthy Han Chinese adults. Since most of these parameters differed by gender and/or age, reference values specified for gender and age should be recommended in clinical practice. Published on behalf of the European Society of Cardiology. All rights reserved.
AIMS: Currently, available Doppler echocardiographic reference values are derived mainly from North American and European population studies, which may not applicable to the Chinese population. We aimed to establish normal reference values of Doppler echocardiographic parameters in a nationwide, population-based cohort of healthy Han Chinese adults. METHODS AND RESULTS: A total of 1394 qualified healthy subjects (mean age 47.3 ± 16.0 years, 678 men) were enrolled at 43 collaborating laboratories, 37 transvalvular flow and tissue Doppler parameters were obtained, and the impacts of gender and age on each parameter were analysed. Significant differences were found between men and women in 48.6% (18/37) of the parameters analysed, and among different age groups in 83.8% (31/37) of the parameters in men and in 86.5% (32/37) of the parameters in women. CONCLUSIONS: Normal reference values of Doppler echocardiographic parameters were established for the first time in a nationwide, population-based cohort of healthy Han Chinese adults. Since most of these parameters differed by gender and/or age, reference values specified for gender and age should be recommended in clinical practice. Published on behalf of the European Society of Cardiology. All rights reserved.
Authors: Hena N Patel; Tatsuya Miyoshi; Karima Addetia; Rodolfo Citro; Masao Daimon; Pedro Gutierrez Fajardo; Ravi R Kasliwal; James N Kirkpatrick; Mark J Monaghan; Denisa Muraru; Kofo O Ogunyankin; Seung Woo Park; Ricardo E Ronderos; Anita Sadeghpour; Gregory M Scalia; Masaaki Takeuchi; Wendy Tsang; Edwin S Tucay; Ana Clara Tude Rodrigues; Vivekanandan Amuthan; Yun Zhang; Marcus Schreckenberg; Michael Blankenhagen; Markus Degel; Niklas Hitschrich; Victor Mor-Avi; Federico M Asch; Roberto M Lang Journal: J Am Soc Echocardiogr Date: 2021-10-04 Impact factor: 7.722