Literature DB >> 26710091

Genetics and neuropsychology: A merger whose time has come.

William S Kremen1, Matthew S Panizzon1, Tyrone D Cannon2.   

Abstract

Genetics and neuropsychology have historically been 2 rather distant and unrelated fields. With the very rapid advances that have been taking place in genetics, research and treatment of disorders of cognition in the 21st century are likely to be increasingly informed by individual differences in genetics and epigenetics. Although neuropsychologists are not expected to become geneticists, it is our view that increased training in genetics should become more central to training in neuropsychology. This relationship should not be unidirectional. Here we note ways in which an understanding of genetics and epigenetics can inform neuropsychology. On the other hand, given the complexity of cognitive phenotypes, neuropsychology can also play a valuable role in informing and refining genetic studies. Greater integration of the 2 should advance both fields. (c) 2015 APA, all rights reserved).

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Year:  2016        PMID: 26710091      PMCID: PMC4758834          DOI: 10.1037/neu0000254

Source DB:  PubMed          Journal:  Neuropsychology        ISSN: 0894-4105            Impact factor:   3.295


  32 in total

1.  Spatial working memory as an endophenotype for schizophrenia.

Authors:  David C Glahn; Sebastian Therman; Marko Manninen; Matti Huttunen; Joakko Kaprio; Jouko Lönnqvist; Tyrone D Cannon
Journal:  Biol Psychiatry       Date:  2003-04-01       Impact factor: 13.382

2.  The association between a polygenic Alzheimer score and cortical thickness in clinically normal subjects.

Authors:  Mert R Sabuncu; Randy L Buckner; Jordan W Smoller; Phil Hyoun Lee; Bruce Fischl; Reisa A Sperling
Journal:  Cereb Cortex       Date:  2011-12-13       Impact factor: 5.357

3.  Contextual genetics.

Authors:  Gerald E McClearn
Journal:  Trends Genet       Date:  2006-05-04       Impact factor: 11.639

4.  Common SNPs explain a large proportion of the heritability for human height.

Authors:  Jian Yang; Beben Benyamin; Brian P McEvoy; Scott Gordon; Anjali K Henders; Dale R Nyholt; Pamela A Madden; Andrew C Heath; Nicholas G Martin; Grant W Montgomery; Michael E Goddard; Peter M Visscher
Journal:  Nat Genet       Date:  2010-06-20       Impact factor: 38.330

5.  Heritability of word recognition in middle-aged men varies as a function of parental education.

Authors:  William S Kremen; Kristen C Jacobson; Hong Xian; Seth A Eisen; Brian Waterman; Rosemary Toomey; Michael C Neale; Ming T Tsuang; Michael J Lyons
Journal:  Behav Genet       Date:  2005-07       Impact factor: 2.805

6.  The inheritance of neuropsychological dysfunction in twins discordant for schizophrenia.

Authors:  T D Cannon; M O Huttunen; J Lonnqvist; A Tuulio-Henriksson; T Pirkola; D Glahn; J Finkelstein; M Hietanen; J Kaprio; M Koskenvuo
Journal:  Am J Hum Genet       Date:  2000-07-03       Impact factor: 11.025

Review 7.  Endophenotypes in the genetic analyses of mental disorders.

Authors:  Tyrone D Cannon; Matthew C Keller
Journal:  Annu Rev Clin Psychol       Date:  2006       Impact factor: 18.561

8.  Genetic risk of neurodegenerative diseases is associated with mild cognitive impairment and conversion to dementia.

Authors:  Hieab H H Adams; Renée F A G de Bruijn; Albert Hofman; André G Uitterlinden; Cornelia M van Duijn; Meike W Vernooij; Peter J Koudstaal; M Arfan Ikram
Journal:  Alzheimers Dement       Date:  2015-04-24       Impact factor: 21.566

9.  Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease.

Authors:  Mike A Nalls; Nathan Pankratz; Christina M Lill; Chuong B Do; Dena G Hernandez; Mohamad Saad; Anita L DeStefano; Eleanna Kara; Jose Bras; Manu Sharma; Claudia Schulte; Margaux F Keller; Sampath Arepalli; Christopher Letson; Connor Edsall; Hreinn Stefansson; Xinmin Liu; Hannah Pliner; Joseph H Lee; Rong Cheng; M Arfan Ikram; John P A Ioannidis; Georgios M Hadjigeorgiou; Joshua C Bis; Maria Martinez; Joel S Perlmutter; Alison Goate; Karen Marder; Brian Fiske; Margaret Sutherland; Georgia Xiromerisiou; Richard H Myers; Lorraine N Clark; Kari Stefansson; John A Hardy; Peter Heutink; Honglei Chen; Nicholas W Wood; Henry Houlden; Haydeh Payami; Alexis Brice; William K Scott; Thomas Gasser; Lars Bertram; Nicholas Eriksson; Tatiana Foroud; Andrew B Singleton
Journal:  Nat Genet       Date:  2014-07-27       Impact factor: 38.330

10.  Gene networks specific for innate immunity define post-traumatic stress disorder.

Authors:  M S Breen; A X Maihofer; S J Glatt; D S Tylee; S D Chandler; M T Tsuang; V B Risbrough; D G Baker; D T O'Connor; C M Nievergelt; C H Woelk
Journal:  Mol Psychiatry       Date:  2015-03-10       Impact factor: 15.992

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  2 in total

1.  Genetic and Environmental Influences on Verbal Fluency in Middle Age: A Longitudinal Twin Study.

Authors:  Daniel E Gustavson; Matthew S Panizzon; Jeremy A Elman; Carol E Franz; Asad Beck; Chandra A Reynolds; Kristen C Jacobson; Hong Xian; Rosemary Toomey; Michael J Lyons; William S Kremen
Journal:  Behav Genet       Date:  2018-06-19       Impact factor: 2.805

2.  Novel functional variants at the GWAS-implicated loci might confer risk to major depressive disorder, bipolar affective disorder and schizophrenia.

Authors:  Leonid O Bryzgalov; Elena E Korbolina; Ilja I Brusentsov; Elena Y Leberfarb; Natalia P Bondar; Tatiana I Merkulova
Journal:  BMC Neurosci       Date:  2018-04-19       Impact factor: 3.288

  2 in total

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