Literature DB >> 26710028

Treatment Outcomes following Traumatic Optic Neuropathy.

Michael Sosin1, Carla De La Cruz, Gerhard S Mundinger, Sean Y Saadat, Arthur J Nam, Paul N Manson, Michael R Christy, Branko Bojovic, Eduardo D Rodriguez.   

Abstract

BACKGROUND: Traumatic optic neuropathy is characterized by sudden loss of vision following facial trauma leading to variable visual deficits. The purpose of this study was to evaluate recent institutional trends in the treatment of traumatic optic neuropathy, evaluate the outcomes of different treatment strategies, and identify factors associated with improved vision.
METHODS: Institutional review board approval was obtained to retrospectively review patients diagnosed with traumatic optic neuropathy at a high-volume trauma center from 2004 to 2012. Pretreatment and posttreatment visual acuity was compared using quantitative analysis of standard ophthalmologic conversion.
RESULTS: A total of 109 patients met inclusion criteria (74.3 percent male patients), with a mean age of 38.0 ± 17.5 years (range, 8 to 82 years). Management of traumatic optic neuropathy involved intravenous corticosteroids alone in 8.3 percent of patients (n = 9), 56.9 percent (n = 62) underwent observation, 28.4 percent (n = 31) had surgical intervention, and 6.4 percent (n = 7) underwent surgery and corticosteroid administration. Only 19.3 percent of patients returned for follow-up. Vision improved in 47.6 percent of patients, with a mean follow-up of 12.9 weeks. Patients younger than 50 years had a trend toward higher rates of visual improvement, 60 percent versus 16.7 percent (p = 0.15).
CONCLUSIONS: The majority of traumatic optic neuropathy patients are unlikely to return for a follow-up examination. Optic nerve decompression has fallen out of favor in the authors' institution, and observation is the most common management strategy. Outcomes following corticosteroid administration and observation are comparable. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV.

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Year:  2016        PMID: 26710028     DOI: 10.1097/PRS.0000000000001907

Source DB:  PubMed          Journal:  Plast Reconstr Surg        ISSN: 0032-1052            Impact factor:   4.730


  7 in total

1.  Combination analysis on the impact of the initial vision and surgical time for the prognosis of indirect traumatic optic neuropathy after endoscopic transnasal optic canal decompression.

Authors:  Wei Yan; Jingquan Lin; Wanglu Hu; Qun Wu; Jianmin Zhang
Journal:  Neurosurg Rev       Date:  2020-02-25       Impact factor: 3.042

2.  Risk factors affecting the visual outcome in patients with indirect traumatic optic neuropathy.

Authors:  Nazife Sefi-Yurdakul; Feray Koç
Journal:  Int Ophthalmol       Date:  2017-07-05       Impact factor: 2.031

Review 3.  Traumatic Optic Neuropathy.

Authors:  Sun Young Jang
Journal:  Korean J Neurotrauma       Date:  2018-04-30

4.  The Alteration of M6A-Tagged Transcript Profiles in the Retina of Rats After Traumatic Optic Neuropathy.

Authors:  Xiaolin Qu; Kaixin Zhu; Zhenxing Li; Danfeng Zhang; Lijun Hou
Journal:  Front Genet       Date:  2021-02-16       Impact factor: 4.599

Review 5.  A Systematic Literature Review on Traumatic Optic Neuropathy.

Authors:  Saeed Karimi; Amir Arabi; Iman Ansari; Toktam Shahraki; Sare Safi
Journal:  J Ophthalmol       Date:  2021-02-26       Impact factor: 1.909

6.  Traumatic Optic Neuropathy Management: A Survey Assessment of Current Practice Patterns.

Authors:  Colin Bacorn; Megan V Morisada; Raj D Dedhia; Toby O Steele; Edward Bradley Strong; Lily Koo Lin
Journal:  J Emerg Trauma Shock       Date:  2021-04-27

7.  Progression of optic atrophy in traumatic optic neuropathy: retrograde neuronal degeneration in humans.

Authors:  Jae Yun Sung; Han Min Lee; Sung Bok Lee; Kyoung Nam Kim; Yeon-Hee Lee
Journal:  Neurol Sci       Date:  2021-07-09       Impact factor: 3.307

  7 in total

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