| Literature DB >> 26707703 |
Yi-Ge Zhou1, Reza M Mohamadi1, Mahla Poudineh2, Leyla Kermanshah3, Sharif Ahmed1, Tina Saberi Safaei2, Jessica Stojcic4, Robert K Nam4, Edward H Sargent2, Shana O Kelley1,3,5.
Abstract
A chip-based approach for electrochemical characterization and detection of microsomes and exosomes based on direct electro-oxidation of metal nanoparticles (MNPs) that specifically recognize surface markers of these vesicles is reported. It is found that exosomes and microsomes derived from prostate cancer cells can be identified by their surface proteins EpCAM and PSMA, suggesting the potential of exosomes and microsomes for use as diagnostic biomarkers.Entities:
Keywords: electrochemistry; exosomes; microsomes; nanoparticles; prostate cancer
Mesh:
Year: 2015 PMID: 26707703 DOI: 10.1002/smll.201502365
Source DB: PubMed Journal: Small ISSN: 1613-6810 Impact factor: 13.281