Literature DB >> 26707070

Methicillin-susceptible strains responsible for postoperative orthopedic infection are not selected by the use of cefazolin in prophylaxis.

Sophie Trouillet-Assant1, Florent Valour2, William Mouton3, Patrícia Martins-Simões3, Sébastien Lustig4, Frédéric Laurent3, Tristan Ferry2.   

Abstract

Comparison of methicillin-susceptible Staphylococcus aureus (MSSA) isolates responsible for bone and joint infection (BJI, n=73) and nasal colonization (n=57) revealed similar prevalence of β-lactamase (blaZ) type A production, associated with cefazolin hydrolysis, suggesting that blaZ type A-carrying MSSA isolates implicated in postoperative BJI are not selected by cefazolin prophylaxis.
Copyright © 2016 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Bone and joint infection; Cefazolin; Prophylaxis; Staphylococcus aureus; β-Lactamase

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Year:  2015        PMID： 26707070     DOI： 10.1016/j.diagmicrobio.2015.11.013

Source DB:  PubMed          Journal:  Diagn Microbiol Infect Dis        ISSN： 0732-8893            Impact factor:   2.803


  1 in total

1.  A Short-Course Antibiotic Prophylaxis Is Associated with Limited Antibiotic Resistance Emergence in Post-Operative Infection of Pelvic Primary Bone Tumor Resection.

Authors:  Yoann Varenne; Stéphane Corvec; Anne-Gaëlle Leroy; David Boutoille; Mỹ-Vân Nguyễn; Sophie Touchais; Pascale Bémer; Antoine Hamel; Denis Waast; Christophe Nich; François Gouin; Vincent Crenn
Journal:  Antibiotics (Basel)       Date:  2021-06-24
  1 in total

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