María Esther Vázquez-López1, Carolina Díez-Morrondo2, Amalia Sánchez-Andrade3, Robustiano Pego-Reigosa4, Pablo Díaz5, Manuel Castro-Gago6. 1. Servicio de Pediatría, Hospital Universitario Lucus Agusti, Lugo, España. Electronic address: esther.vazquez.lopez@sergas.es. 2. Unidad de Reumatología, Hospital del Bierzo, Ponferrada, León, España. 3. Servicio de Reumatología, Hospital Universitario Lucus Agusti, Lugo, España. 4. Servicio de Neurología, Hospital Universitario Lucus Agusti, Lugo, España. 5. Unidad de Epidemiología, Zoonosis y Salud Pública, Facultad de Veterinaria, Universidad de Santiago de Compostela, Lugo, España. 6. Servicio de Neuropediatría, Hospital Clínico Universitario, Santiago de Compostela, La Coruña, España.
Abstract
OBJECTIVES: To determine the percentage of Lyme patients with articular manifestations in NW Spain and to know their evolution and response to treatment. PATIENTS: A retrospective study (2006-2013) was performed using medical histories of confirmed cases of Lyme disease showing articular manifestations. Clinical and laboratory characteristics, together with the treatment and evolution of the patients, were analysed. RESULTS: Seventeen out of 108 LD confirmed patients (15.7%) showed articular manifestations. Regarding those 17 patients, 64.7%, 29.4% and 5.9% presented arthritis, arthralgia and bursitis, respectively. The knee was the most affected joint. Articular manifestations were often associated to neurological, dermatological and cardiac pathologies. Otherwise, most patients were in Stage III. The 11.8% of the cases progressed to a recurrent chronic arthritis despite the administration of an appropriate treatment. CONCLUSIONS: Lyme disease patients showing articular manifestations should be included in the diagnosis of articular affections in areas of high risk of hard tick bite, in order to establish a suitable and early treatment and to avoid sequels.
OBJECTIVES: To determine the percentage of Lyme patients with articular manifestations in NW Spain and to know their evolution and response to treatment. PATIENTS: A retrospective study (2006-2013) was performed using medical histories of confirmed cases of Lyme disease showing articular manifestations. Clinical and laboratory characteristics, together with the treatment and evolution of the patients, were analysed. RESULTS: Seventeen out of 108 LD confirmed patients (15.7%) showed articular manifestations. Regarding those 17 patients, 64.7%, 29.4% and 5.9% presented arthritis, arthralgia and bursitis, respectively. The knee was the most affected joint. Articular manifestations were often associated to neurological, dermatological and cardiac pathologies. Otherwise, most patients were in Stage III. The 11.8% of the cases progressed to a recurrent chronic arthritis despite the administration of an appropriate treatment. CONCLUSIONS:Lyme diseasepatients showing articular manifestations should be included in the diagnosis of articular affections in areas of high risk of hard tick bite, in order to establish a suitable and early treatment and to avoid sequels.
Authors: Pablo Díaz; Jose Luis Arnal; Susana Remesar; Ana Pérez-Creo; José Manuel Venzal; María Esther Vázquez-López; Alberto Prieto; Gonzalo Fernández; Ceferino Manuel López; Rosario Panadero; Alfredo Benito; Pablo Díez-Baños; Patrocinio Morrondo Journal: Parasit Vectors Date: 2017-12-20 Impact factor: 3.876