Literature DB >> 2670534

Intermittent home treatment of status and clusters of seizures.

C T Lombroso1.   

Abstract

Clinical trials in children and adults indicate that the intermittent oral or rectal administration of diazepam is an effective and safe alternative for the acute management of recurrent paroxysmal disorders. Prompt home treatment of dangerous or upsetting relapses can prevent the morbid effects of prolonged seizures and offer the patients and their families a sense of control over the illness.

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Year:  1989        PMID： 2670534     DOI： 10.1111/j.1528-1157.1989.tb05819.x

Source DB:  PubMed          Journal:  Epilepsia        ISSN： 0013-9580            Impact factor:   5.864


  9 in total

Review 1.  Fosphenytoin: clinical pharmacokinetics and comparative advantages in the acute treatment of seizures.

Authors:  James H Fischer; Tejal V Patel; Patricia A Fischer
Journal:  Clin Pharmacokinet       Date:  2003       Impact factor: 6.447

2.  Pharmacokinetics of diazepam administered intramuscularly by autoinjector versus rectal gel in healthy subjects: a phase I, randomized, open-label, single-dose, crossover, single-centre study.

Authors:  Michael J Lamson; Diane Sitki-Green; Gerald L Wannarka; Michael Mesa; Paul Andrews; John Pellock
Journal:  Clin Drug Investig       Date:  2011       Impact factor: 2.859

Review 3.  Generalized convulsive status epilepticus: pathophysiology and treatment.

Authors:  F B Scholtes; W O Renier; H Meinardi
Journal:  Pharm World Sci       Date:  1993-02-19

4.  Comparison of intranasal midazolam with intravenous diazepam for treating febrile seizures in children: prospective randomised study.

Authors:  E Lahat; M Goldman; J Barr; T Bistritzer; M Berkovitch
Journal:  BMJ       Date:  2000-07-08

5.  A randomized controlled trial of intranasal-midazolam versus intravenous-diazepam for acute childhood seizures.

Authors:  Arpita Thakker; Preeti Shanbag
Journal:  J Neurol       Date:  2012-09-16       Impact factor: 4.849

6.  Lack of clinically relevant differences in safety and pharmacokinetics after second-dose administration of intranasal diazepam within 4 h for acute treatment of seizure clusters: A population analysis.

Authors:  Gregory D Cascino; Daniel Tarquinio; James W Wheless; Robert Edward Hogan; Michael R Sperling; Jay Desai; Blanca Vazquez; Emil Samara; Sunita N Misra; Enrique Carrazana; Adrian L Rabinowicz
Journal:  Epilepsia       Date:  2022-04-19       Impact factor: 6.740

Review 7.  Rescue therapies for seizure clusters: Pharmacology and target of treatments.

Authors:  Barry Gidal; Kamil Detyniecki
Journal:  Epilepsia       Date:  2022-09       Impact factor: 6.740

8.  Comparison of intravenous midazolam drip with intermittent intravenous diazepam in the treatment of refractory serial seizures in children.

Authors:  Afshin Fa Yyazi; Parvaneh Karimzadeh; Saadat Torabian; Somayeh Damadi; Ali Khajeh
Journal:  Iran J Child Neurol       Date:  2012

9.  Use of second doses of Valtoco® (diazepam nasal spray) across 24 hours after the initial dose for out-of-hospital seizure clusters: Results from a phase 3, open-label, repeat-dose safety study.

Authors:  Michael R Sperling; James W Wheless; R Edward Hogan; Dennis Dlugos; Gregory D Cascino; Kore Liow; Adrian L Rabinowicz; Enrique Carrazana
Journal:  Epilepsia       Date:  2022-02-02       Impact factor: 6.740
  9 in total

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