M Spahn1, S Boxler2. 1. Urologische Universitätsklinik, Inselspital Bern, Anna Seiler-Haus, CH-3010, Bern, Schweiz. martin.spahn@insel.ch. 2. Urologische Universitätsklinik, Inselspital Bern, Anna Seiler-Haus, CH-3010, Bern, Schweiz.
Abstract
BACKGROUND: Bladder cancer represents one of the ten most prevalent cancers worldwide. More than 400,000 people worldwide are newly diagnosed every year. Within 2 years after diagnosis, 80% of patients with muscle invasive bladder cancer without treatment die. METHODS: The aggressive local surgical approach with a cystectomy is the therapy of choice. The median age of patients with de novo bladder cancer is 70 years. Thus bladder cancer is a cancer of the elderly. For demographical reasons, the number of eldery patients undergoing radical cystectomy will rise in the next few years. The type of urinary diversion is a major factor influencing perioperative morbidity and quality of life in these patients. Incontinent urinary diversions are preferentially used in daily practice. CONCLUSIONS: There are only a few contraindications for orthotopic neobladder; however, age alone is not a contraindication. Patient selection and a nerve sparing approach are crucial in men and women to achieve excellent functional results with orthotopic neobladder in elderly patients.
BACKGROUND:Bladder cancer represents one of the ten most prevalent cancers worldwide. More than 400,000 people worldwide are newly diagnosed every year. Within 2 years after diagnosis, 80% of patients with muscle invasive bladder cancer without treatment die. METHODS: The aggressive local surgical approach with a cystectomy is the therapy of choice. The median age of patients with de novo bladder cancer is 70 years. Thus bladder cancer is a cancer of the elderly. For demographical reasons, the number of eldery patients undergoing radical cystectomy will rise in the next few years. The type of urinary diversion is a major factor influencing perioperative morbidity and quality of life in these patients. Incontinent urinary diversions are preferentially used in daily practice. CONCLUSIONS: There are only a few contraindications for orthotopic neobladder; however, age alone is not a contraindication. Patient selection and a nerve sparing approach are crucial in men and women to achieve excellent functional results with orthotopic neobladder in elderly patients.
Authors: Wassim Kassouf; Richard E Hautmann; Bernard H Bochner; Seth P Lerner; Renzo Colombo; Alexandre Zlotta; Urs E Studer Journal: Eur Urol Date: 2010-05-22 Impact factor: 20.096
Authors: Peter E Clark; John P Stein; Susan G Groshen; Jie Cai; Gus Miranda; Gary Lieskovsky; Donald G Skinner Journal: Cancer Date: 2005-07-01 Impact factor: 6.860