Brian C Gulack1, Matthew M Laughon2, Reese H Clark3, Terrance Burgess4, Sybil Robinson4, Abdurrauf Muhammad4, Angela Zhang4, Adrienne Davis4, Robert Morton4, Vivian H Chu5, Christopher J Arnold5, Christoph P Hornik6, P Brian Smith7. 1. Department of Surgery, Duke University Medical Center, Durham, NC; Duke Clinical Research Institute, Duke University Medical Center, Durham, NC. 2. Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, NC. 3. Pediatrix Medical Group, Inc, Sunrise, FL. 4. Duke Clinical Research Institute, Duke University Medical Center, Durham, NC. 5. Department of Medicine, Duke University Medical Center, Durham, NC. 6. Duke Clinical Research Institute, Duke University Medical Center, Durham, NC; Department of Pediatrics, Duke University Medical Center, Durham, NC. 7. Duke Clinical Research Institute, Duke University Medical Center, Durham, NC; Department of Pediatrics, Duke University Medical Center, Durham, NC. Electronic address: brian.smith@duke.edu.
Abstract
OBJECTIVE: To assess the effect of enteral feeding with human milk on the time from initiation of feeds to discharge after gastroschisis repair through review of a multi-institutional database. STUDY DESIGN: Infants who underwent gastroschisis repair between 1997 and 2012 with data recorded in the Pediatrix Medical Group Clinical Data Warehouse were categorized into 4 groups based on the percentage of days fed human milk out of the number of days fed enterally. Cox proportional hazards regression modeling was performed to determine the adjusted effect of human milk on the time from initiation of feeds to discharge. RESULTS: Among 3082 infants, 659 (21%) were fed human milk on 0% of enteral feeding days, 766 (25%) were fed human milk on 1%-50% of enteral feeding days, 725 (24%) were fed human milk on 51%-99% of enteral feeding days, and 932 (30%) were fed human milk on 100% of enteral feeding days. Following adjustment, being fed human milk on 0% of enteral feeding days was associated with a significantly increased time to discharge compared with being fed human milk on 100% of enteral feeding days (hazard ratio [HR] for discharge per day, 0.46; 95% CI, 0.40-0.52). The same was found for infants fed human milk on 1%-50% of enteral feeding days (HR, 0.37; 95% CI, 0.32-0.41) and for infants fed human milk on 51%-99% of enteral feeding days (HR, 0.51; 95% CI, 0.46-0.57). CONCLUSION: The use of human milk for enteral feeding of infants following repair of gastroschisis significantly reduces the time to discharge from initiation of feeds.
OBJECTIVE: To assess the effect of enteral feeding with human milk on the time from initiation of feeds to discharge after gastroschisis repair through review of a multi-institutional database. STUDY DESIGN: Infants who underwent gastroschisis repair between 1997 and 2012 with data recorded in the Pediatrix Medical Group Clinical Data Warehouse were categorized into 4 groups based on the percentage of days fed human milk out of the number of days fed enterally. Cox proportional hazards regression modeling was performed to determine the adjusted effect of human milk on the time from initiation of feeds to discharge. RESULTS: Among 3082 infants, 659 (21%) were fed human milk on 0% of enteral feeding days, 766 (25%) were fed human milk on 1%-50% of enteral feeding days, 725 (24%) were fed human milk on 51%-99% of enteral feeding days, and 932 (30%) were fed human milk on 100% of enteral feeding days. Following adjustment, being fed human milk on 0% of enteral feeding days was associated with a significantly increased time to discharge compared with being fed human milk on 100% of enteral feeding days (hazard ratio [HR] for discharge per day, 0.46; 95% CI, 0.40-0.52). The same was found for infants fed human milk on 1%-50% of enteral feeding days (HR, 0.37; 95% CI, 0.32-0.41) and for infants fed human milk on 51%-99% of enteral feeding days (HR, 0.51; 95% CI, 0.46-0.57). CONCLUSION: The use of human milk for enteral feeding of infants following repair of gastroschisis significantly reduces the time to discharge from initiation of feeds.
Authors: Aline Andres; Mario A Cleves; Jayne B Bellando; R T Pivik; Patrick H Casey; Thomas M Badger Journal: Pediatrics Date: 2012-05-28 Impact factor: 7.124
Authors: Rebecca B Russell; Nancy S Green; Claudia A Steiner; Susan Meikle; Jennifer L Howse; Karalee Poschman; Todd Dias; Lisa Potetz; Michael J Davidoff; Karla Damus; Joann R Petrini Journal: Pediatrics Date: 2007-07 Impact factor: 7.124
Authors: Andrew P Storm; Rakhee M Bowker; Samuel C Klonoski; Stephanie E Iantorno; Ami N Shah; Srikumar Pillai; Jonathan Bell; Aloka L Patel Journal: J Perinatol Date: 2020-01-28 Impact factor: 2.521