Synthesis and catalytic applications of C3-symmetric tris(triazolyl)methanol ligands and derivatives.

Recently introduced tris(1,2,3-triazol-4-yl)methanols and derivatives (TTM ligands) have become a valuable subclass of C3-symmetric tripodal ligands for transition metal-mediated reactions. TTM-based ligand architectures are modularly constructed through regioselective, one-pot triple [3+2] cycloaddition of azides and alkynes. Applications of homogeneous systems of this type and of heterogenised (polystyrene- and magnetic nanoparticle-supported) TTM ligands in synthesis and catalysis are compiled in this Feature Article.