| Literature DB >> 26700189 |
Bing Peng1, Rui-Feng Bai2, Ping Li1, Xu-Yang Han1, Hong Wang1, Chong-Chong Zhu1, Zu-Ping Zeng1, Xing-Yun Chai2.
Abstract
Phytochemical investigation on the aqueous extract from Dryopteris fragrans led to the isolation of one new chromone glycoside, frachromone C (1), and one new coumarin glycoside, dryofracoulin A (2), together with one known undulatoside A (3). Their structures were elucidated by a combination of 1D and 2D NMR, HRMS, and chemical analysis. Compounds 1-3 exhibited inhibition on nitric oxide production in lipopolysaccharide induced RAW 264.7 macrophages with their IC50 values of 45.8, 65.8, and 49.8 μM, respectively.Entities:
Keywords: Dryopteridaceae; Dryopteris fragrans; anti-inflammatory activity; isolation; structure elucidation
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Year: 2015 PMID: 26700189 DOI: 10.1080/10286020.2015.1121853
Source DB: PubMed Journal: J Asian Nat Prod Res ISSN: 1028-6020 Impact factor: 1.569