Literature DB >> 26699746

Triglyceride-Lowering Effects of Two Probiotics, Lactobacillus plantarum KY1032 and Lactobacillus curvatus HY7601, in a Rat Model of High-Fat Diet-Induced Hypertriglyceridemia.

Il-Dong Choi1, Sung-Hwan Kim1, Ji-Woong Jeong1, Dong Eun Lee1, Chul-Sung Huh2, Seong Soo Hong3, Jae-Hun Sim1, Young-Tae Ahn1.   

Abstract

The triglyceride-lowering effect of probiotics Lactobacillus plantarum KY1032 and Lactobacillus curvatus HY7601 were investigated. Male SD Wistar rats were randomly divided into three groups and fed high-fat diet (HFD), HFD and probiotics (5 X 10(9) CFU/day of L. plantarum KY1032 and 5 X 10(9) CFU/day of L. curvatus HY7601), or normal diet for 6 weeks. Probiotic treatment significantly lowered the elevated plasma triglyceride and increased plasma free fatty acid, glycerol, and plasma apolipoprotein A-V (ApoA-V) levels. The probiotic-treated group showed elevated hepatic mRNA expression of PPARα, bile acid receptor (FXR), and ApoA-V. These results demonstrate that L. plantarum KY1032 and L. curvatus HY7601 lower triglycerides in hypertriglyceridemic rats by upregulating ApoA-V, PPARα, and FXR.

Entities:  

Keywords:  Lactobacillus curvatus; Lactobacillus plantarum; Triglyceride; apolipoprotein A-V; probiotics

Mesh：

Substances：

Year:  2016        PMID： 26699746     DOI： 10.4014/jmb.1512.12018

Source DB:  PubMed          Journal:  J Microbiol Biotechnol        ISSN： 1017-7825            Impact factor:   2.351


  5 in total

1.  Probiotic Characteristics of Lactobacillus curvatus DN317, a Strain Isolated from Chicken Ceca.

Authors:  Mohamed Zommiti; Nathalie Connil; Jeannette Ben Hamida; Mounir Ferchichi
Journal:  Probiotics Antimicrob Proteins       Date:  2017-12       Impact factor: 4.609

2.  Effects of Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032 on Overweight and the Gut Microbiota in Humans: Randomized, Double-Blinded, Placebo-Controlled Clinical Trial.

Authors:  Sung-Joon Mo; Kippeum Lee; Hyoung-Ju Hong; Dong-Ki Hong; Seung-Hee Jung; Soo-Dong Park; Jae-Jung Shim; Jung-Lyoul Lee
Journal:  Nutrients       Date:  2022-06-15       Impact factor: 6.706

3.  Dietary lipid content reorganizes gut microbiota and probiotic L. rhamnosus attenuates obesity and enhances catabolic hormonal milieu in zebrafish.

Authors:  Silvia Falcinelli; Ana Rodiles; Azadeh Hatef; Simona Picchietti; Lina Cossignani; Daniel L Merrifield; Suraj Unniappan; Oliana Carnevali
Journal:  Sci Rep       Date:  2017-07-17       Impact factor: 4.379

4.  Gut Microbiome Associates With Lipid-Lowering Effect of Rosuvastatin in Vivo.

Authors:  Yinhui Liu; Xiaobo Song; Huimin Zhou; Xue Zhou; Yunlong Xia; Xin Dong; Wei Zhong; Shaoying Tang; Lili Wang; Shu Wen; Jing Xiao; Li Tang
Journal:  Front Microbiol       Date:  2018-03-22       Impact factor: 5.640

5.  Eggshell membrane powder lowers plasma triglyceride and liver total cholesterol by modulating gut microbiota and accelerating lipid metabolism in high-fat diet-fed mice.

Authors:  Nurul Shazini Ramli; Huijuan Jia; Ayumu Sekine; Weida Lyu; Kyohei Furukawa; Kenji Saito; Yukio Hasebe; Hisanori Kato
Journal:  Food Sci Nutr       Date:  2020-04-05       Impact factor: 2.863
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.