Literature DB >> 26698730

Mass-manufacturable polymer microfluidic device for dual fiber optical trapping.

Diane De Coster, Heidi Ottevaere, Michael Vervaeke, Jürgen Van Erps, Manly Callewaert, Pieter Wuytens, Stephen H Simpson, Simon Hanna, Wim De Malsche, Hugo Thienpont.   

Abstract

We present a microfluidic chip in Polymethyl methacrylate (PMMA) for optical trapping of particles in an 80µm wide microchannel using two counterpropagating single-mode beams. The trapping fibers are separated from the sample fluid by 70µm thick polymer walls. We calculate the optical forces that act on particles flowing in the microchannel using wave optics in combination with non-sequential ray-tracing and further mathematical processing. Our results are compared with a theoretical model and the Mie theory. We use a novel fabrication process that consists of a premilling step and ultraprecision diamond tooling for the manufacturing of the molds and double-sided hot embossing for replication, resulting in a robust microfluidic chip for optical trapping. In a proof-of-concept demonstration, we show the trapping capabilities of the hot embossed chip by trapping spherical beads with a diameter of 6µm, 8µm and 10µm and use the power spectrum analysis of the trapped particle displacements to characterize the trap strength.

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Year:  2015        PMID: 26698730     DOI: 10.1364/OE.23.030991

Source DB:  PubMed          Journal:  Opt Express        ISSN: 1094-4087            Impact factor:   3.894


  3 in total

1.  Disposable Optical Stretcher Fabricated by Microinjection Moulding.

Authors:  Gianluca Trotta; Rebeca Martínez Vázquez; Annalisa Volpe; Francesco Modica; Antonio Ancona; Irene Fassi; Roberto Osellame
Journal:  Micromachines (Basel)       Date:  2018-08-04       Impact factor: 2.891

Review 2.  Particle Manipulation by Optical Forces in Microfluidic Devices.

Authors:  Petra Paiè; Tommaso Zandrini; Rebeca Martínez Vázquez; Roberto Osellame; Francesca Bragheri
Journal:  Micromachines (Basel)       Date:  2018-04-24       Impact factor: 2.891

3.  3D printed microfluidic lab-on-a-chip device for fiber-based dual beam optical manipulation.

Authors:  Haoran Wang; Anton Enders; John-Alexander Preuss; Janina Bahnemann; Alexander Heisterkamp; Maria Leilani Torres-Mapa
Journal:  Sci Rep       Date:  2021-07-16       Impact factor: 4.379

  3 in total

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