Literature DB >> 26698204

Outcome of cataract surgery following simple limbal epithelial transplantation for lime injury-induced limbal stem cell deficiency.

Dhanyasree Nair1, Ashik Mohamed2, Virender S Sangwan1.   

Abstract

A 19-year-old woman presented to us after being diagnosed elsewhere with right eye total limbal stem cell deficiency resulting from a lime burn. She was advised to undergo limbal stem cell transplantation, but failed to immediately do so. Two years later, she underwent cultivated limbal epithelial transplantation (CLET). As she had severe loss of vision with persisting conjunctival nodule and symblepharon 2 years following surgery, an impression of failed CLET was formed. Subsequently, simple limbal epithelial transplantation (SLET) was performed. Nine months later, she developed a cataract in her right eye; the cataract was extracted and posterior chamber intraocular lens implanted. The unaided visual acuity improved from light perception at presentation to 20/60 at 1-week postoperatively. At 5 months follow-up, the patient continued to maintain 20/60 visual acuity in her right eye. This case describes the outcome of cataract surgery following SLET, emphasising the need to perform cataract surgery in complicated cataracts for a better visual prognosis. 2015 BMJ Publishing Group Ltd.

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Year:  2015        PMID: 26698204      PMCID: PMC4691855          DOI: 10.1136/bcr-2015-212613

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  4 in total

1.  Simple limbal epithelial transplantation (SLET): a novel surgical technique for the treatment of unilateral limbal stem cell deficiency.

Authors:  Virender S Sangwan; Sayan Basu; Sheila MacNeil; Dorairajan Balasubramanian
Journal:  Br J Ophthalmol       Date:  2012-02-10       Impact factor: 4.638

2.  [Intraocular complications after severe chemical burns--incidence and surgical treatment].

Authors:  R Kuckelkorn; A Kottek; M Reim
Journal:  Klin Monbl Augenheilkd       Date:  1994-08       Impact factor: 0.700

3.  Epidemiology and Outcome of Chemical Burn Patients Admitted in Burn Unit of JNMC Hospital, Aligarh Muslim University, Aligarh, Uttar Pradesh, India: A 5-year Experience.

Authors:  Md Sohaib Akhtar; Imran Ahmad; M Fahud Khurram; Srikanta Kanungo
Journal:  J Family Med Prim Care       Date:  2015 Jan-Mar

Review 4.  Ocular chemical injuries and their management.

Authors:  Parul Singh; Manoj Tyagi; Yogesh Kumar; K K Gupta; P D Sharma
Journal:  Oman J Ophthalmol       Date:  2013-05
  4 in total
  4 in total

Review 1.  Twenty years of limbal epithelial therapy: an update on managing limbal stem cell deficiency.

Authors:  Roberto Fernandez-Buenaga; Francesco Aiello; Sarah S Zaher; Andre Grixti; Sajjad Ahmad
Journal:  BMJ Open Ophthalmol       Date:  2018-08-10

Review 2.  Simple limbal epithelial transplantation: Current status and future perspectives.

Authors:  Catherine J Jackson; Inger T Myklebust Ernø; Håkon Ringstad; Kim A Tønseth; Darlene A Dartt; Tor P Utheim
Journal:  Stem Cells Transl Med       Date:  2019-12-04       Impact factor: 6.940

Review 3.  Recent Advances in Stem Cell Therapy for Limbal Stem Cell Deficiency: A Narrative Review.

Authors:  Ali E Ghareeb; Majlinda Lako; Francisco C Figueiredo
Journal:  Ophthalmol Ther       Date:  2020-09-24

Review 4.  Economic, clinical and social impact of simple limbal epithelial transplantation for limbal stem cell deficiency.

Authors:  Praveen Thokala; Aastha Singh; Vijay Kumar Singh; Varsha M Rathi; Sayan Basu; Vivek Singh; Sheila MacNeil; Virender Singh Sangwan
Journal:  Br J Ophthalmol       Date:  2021-03-09       Impact factor: 5.908

  4 in total

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