Literature DB >> 26698033

Risk assessment and risk scores in the management of aortic aneurysms.

Gerdine C I Von Meijenfeldt1, Maarten J Van Der Laan, Clark J Zeebregts, Ron Balm, Hence J M Verhagen.   

Abstract

The decision whether to operate a patient or not can be challenging for a clinician for both ruptured abdominal aortic aneurysms (AAAs) as well as elective AAAs. Prior to surgical intervention it would be preferable that the clinician exactly knows which clinical variables lower or increase the chances of morbidity and mortality postintervention. To help in the preoperative counselling and shared decision making several clinical variables can be identified as risk factors and with these, risk models can be developed. An ideal risk score for aneurysm repair includes routinely obtained physiological and anatomical variables, has excellent discrimination and calibration, and is validated in different geographical areas. For elective AAA repair, several risk scores are available, for ruptured AAA treatment, these scores are far less well developed. In this manuscript, we describe the designs and results of published risk scores for elective and open repair. Also, suggestions for uniformly reporting of risk factors and their statistical analyses are described. Furthermore, the preliminary results of a new risk model for ruptured aortic aneurysm will be discussed. This score identifies age, hemoglobin, cardiopulmonary resuscitation and preoperative systolic blood pressure as risk factors after multivariate regression analysis. This new risk score can help to identify patients that would not benefit from repair, but it can also potentially identify patients who would benefit and therefore lower turndown rates. The challenge for further research is to expand on validation of already existing promising risk scores in order to come to a risk model with optimal discrimination and calibration.

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Year:  2015        PMID: 26698033

Source DB:  PubMed          Journal:  J Cardiovasc Surg (Torino)        ISSN: 0021-9509            Impact factor:   1.888


  2 in total

1.  Nutritional status and out-of-hospital mortality in vascular surgery patients.

Authors:  G C I von Meijenfeldt; K M Mogensen; M J van der Laan; C J Zeebregts; K B Christopher
Journal:  PLoS One       Date:  2022-07-21       Impact factor: 3.752

2.  Red cell distribution width at hospital discharge and out-of hospital outcomes in critically ill non-cardiac vascular surgery patients.

Authors:  Gerdine C I von Meijenfeldt; Maarten J van der Laan; Clark J A M Zeebregts; Kenneth B Christopher
Journal:  PLoS One       Date:  2018-09-05       Impact factor: 3.240

  2 in total

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