Literature DB >> 26697835

AKT-driven phospho-patterns of pluripotency.

Thorsten Schaefer1, Claudia Lengerke1,2.   

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Year:  2015        PMID： 26697835      PMCID： PMC4825714          DOI： 10.1080/15384101.2015.1115642

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  7 in total

1.  Phosphorylation of Sox2 cooperates in reprogramming to pluripotent stem cells.

Authors:  Chul-Ho Jeong; Yong-Yeon Cho; Myoung-Ok Kim; Sung-Hyun Kim; Eun-Jin Cho; Sung-Young Lee; Young-Jin Jeon; Kun Yeong Lee; Ke Yao; Young-Sam Keum; Ann M Bode; Zigang Dong
Journal:  Stem Cells       Date:  2010-12       Impact factor: 6.277

2.  Novel AKT phosphorylation sites identified in the pluripotency factors OCT4, SOX2 and KLF4.

Authors:  Peter N Malak; Benjamin Dannenmann; Alexander Hirth; Oliver C Rothfuss; Klaus Schulze-Osthoff
Journal:  Cell Cycle       Date:  2015       Impact factor: 4.534

3.  Activation of Akt signaling is sufficient to maintain pluripotency in mouse and primate embryonic stem cells.

Authors:  S Watanabe; H Umehara; K Murayama; M Okabe; T Kimura; T Nakano
Journal:  Oncogene       Date:  2006-05-04       Impact factor: 9.867

4.  Reciprocal regulation of Akt and Oct4 promotes the self-renewal and survival of embryonal carcinoma cells.

Authors:  Yuanji Lin; Ying Yang; Weihua Li; Qi Chen; Jie Li; Xiao Pan; Lina Zhou; Changwei Liu; Chunsong Chen; Jianqin He; Hongcui Cao; Hangping Yao; Li Zheng; Xiaowei Xu; Zongping Xia; Jiangtao Ren; Lei Xiao; Lanjuan Li; Binghui Shen; Honglin Zhou; Ying-Jie Wang
Journal:  Mol Cell       Date:  2012-10-04       Impact factor: 17.970

5.  DC120, a novel AKT inhibitor, preferentially suppresses nasopharyngeal carcinoma cancer stem-like cells by downregulating Sox2.

Authors:  Juan Qin; Jiao Ji; Rong Deng; Jun Tang; Fen Yang; Gong-Kan Feng; Wen-Dan Chen; Xiao-Qi Wu; Xiao-Jun Qian; Ke Ding; Xiao-Feng Zhu
Journal:  Oncotarget       Date:  2015-03-30

6.  Akt-signal integration is involved in the differentiation of embryonal carcinoma cells.

Authors:  Bo Chen; Zheng Xue; Guanghui Yang; Bingyang Shi; Ben Yang; Yuemin Yan; Xue Wang; Daishu Han; Yue Huang; Wenji Dong
Journal:  PLoS One       Date:  2013-06-06       Impact factor: 3.240

7.  Molecular and functional interactions between AKT and SOX2 in breast carcinoma.

Authors:  Thorsten Schaefer; Hui Wang; Perihan Mir; Martina Konantz; Tamara C Pereboom; Anna M Paczulla; Britta Merz; Tanja Fehm; Sven Perner; Oliver C Rothfuss; Lothar Kanz; Klaus Schulze-Osthoff; Claudia Lengerke
Journal:  Oncotarget       Date:  2015-12-22
  7 in total
  2 in total

Review 1.  SOX2 protein biochemistry in stemness, reprogramming, and cancer: the PI3K/AKT/SOX2 axis and beyond.

Authors:  Thorsten Schaefer; Claudia Lengerke
Journal:  Oncogene       Date:  2019-09-02       Impact factor: 9.867

2.  Targeting therapy-resistant lung cancer stem cells via disruption of the AKT/TSPYL5/PTEN positive-feedback loop.

Authors:  In-Gyu Kim; Jei-Ha Lee; Seo-Yeon Kim; Chang-Kyu Heo; Rae-Kwon Kim; Eun-Wie Cho
Journal:  Commun Biol       Date:  2021-06-23
  2 in total

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