Literature DB >> 26697756

Diabetes and Glucose Metabolism in Thalassemia Major: An Update.

Vincenzo De Sanctis1, Ashraf T Soliman2, Heba Elsedfy3, Alessia Pepe4, Christos Kattamis5, Mohamed El Kholy3, Mohamed Yassin6.   

Abstract

In patients with TM, uncontrolled iron overload has serious clinical consequences with considerable morbidity and mortality. Complications include liver damage, cardiac disease and endocrine dysfunction. Diabetes is an important complication of TM. The mechanisms of abnormal glucose homeostasis are complex and multifactorial. This review updates the current knowledge about glycemic abnormalities in TM patients and directs the attention to an early diagnosis and proper management.

Entities:  

Keywords:  Continuous glucose monitoring system; Glucose homeostasis; Iron overload; Magnetic resonance imaging; Thalassemia; Treatment

Mesh：

Substances：

Year:  2016        PMID： 26697756     DOI： 10.1586/17474086.2016.1136209

Source DB:  PubMed          Journal:  Expert Rev Hematol        ISSN： 1747-4094            Impact factor:   2.929


  17 in total

1.  Combating iron overload: a case for deferoxamine-based nanochelators.

Authors:  Gregory Jones; Sumanta Kumar Goswami; Homan Kang; Hak Soo Choi; Jonghan Kim
Journal:  Nanomedicine (Lond)       Date:  2020-05-20       Impact factor: 5.307

2.  Increased mitochondrial DNA deletions and copy number in transfusion-dependent thalassemia.

Authors:  Ashutosh Lal; Esteban Gomez; Cassandra Calloway
Journal:  JCI Insight       Date:  2016-08-04

3.  Metabolomic Investigation of β-Thalassemia in Chorionic Villi Samples.

Authors:  Giovanni Monni; Federica Murgia; Valentina Corda; Cristina Peddes; Ambra Iuculano; Laura Tronci; Antonella Balsamo; Luigi Atzori
Journal:  J Clin Med       Date:  2019-06-05       Impact factor: 4.241

4.  The effect of zinc deficiency and iron overload on endocrine and exocrine pancreatic function in children with transfusion-dependent thalassemia: a cross-sectional study.

Authors:  Suzan O Mousa; Ebtihal M Abd Alsamia; Hend M Moness; Osama G Mohamed
Journal:  BMC Pediatr       Date:  2021-10-22       Impact factor: 2.125

5.  Low back pain in beta thalassemia major revealing sacral extramedullay hematopoeisis: A case report.

Authors:  Rita W Ahmad; Lina A Okar; Abdelhaleem Elhiday; Hussam Almasri; Fateen Ata; Elsayed Ahmed Mounir; Ali Barah; Mohamed Abdelrazek; Amna Gamil; Mouhammad Z Sharaf Eldean; Mohamed A Yassin
Journal:  Clin Case Rep       Date:  2021-05-24

6.  The ICET-A Recommendations for the Diagnosis and Management of Disturbances of Glucose Homeostasis in Thalassemia Major Patients.

Authors:  Vincenzo De Sanctis; Ashraf T Soliman; Heba Elsedfy; Saif Al Yaarubi; Nicos Skordis; Doaa Khater; Mohamed El Kholy; Iva Stoeva; Bernadette Fiscina; Michael Angastiniotis; Shahina Daar; Christos Kattamis
Journal:  Mediterr J Hematol Infect Dis       Date:  2016-10-28       Impact factor: 2.576

Review 7.  Review and Recommendations on Management of Adult Female Thalassemia Patients with Hypogonadism based on Literature Review and Experience of ICET-A Network Specialists.

Authors:  Vincenzo De Sanctis; Ashraf T Soliman; Heba Elsedfy; Alice Albu; Soad Al Jaouni; Salvatore Anastasi; Maria Grazia Bisconte; Duran Canatan; Soteroula Christou; Shahina Daar; Salvatore Di Maio; Mohamed El Kholy; Doaa Khater; Mohamed Elshinawy; Yurdanur Kilinc; Roberto Mattei; Hala H Mosli; Alessandra Quota; Maria Grazia Roberti; Praveen Sobti; Saif Al Yaarubi; Saveria Canpisi; Christos Kattamis
Journal:  Mediterr J Hematol Infect Dis       Date:  2017-01-01       Impact factor: 2.576

8.  β-Thalassemia Patients Revealed a Significant Change of Untargeted Metabolites in Comparison to Healthy Individuals.

Authors:  Syed Ghulam Musharraf; Ayesha Iqbal; Saqib Hussain Ansari; Sadia Parveen; Ishtiaq Ahmad Khan; Amna Jabbar Siddiqui
Journal:  Sci Rep       Date:  2017-02-13       Impact factor: 4.379

9.  Retrospective Analysis of Endocrine Dysfunctions in a Population of Adult Polytransfused Patients: Correlation of GH-IGF1 Axis Alteration with Cardiac Performance.

Authors:  Michela Rosaria Campo; Anna Farese; Michele Correale; Giuseppe Berti; Michela Massa; Maria Rosaria Sorrentino; Grazia Roberti; Filomena Sportelli; Mauro Cignarelli; Olga Lamacchia
Journal:  Biomed Res Int       Date:  2018-09-26       Impact factor: 3.411

10.  The Impact of Iron Overload in Patients with Acute Leukemia and Myelodysplastic Syndrome on Hepatic and Endocrine functions.

Authors:  Mohamed A Yassin; Ashraf Soliman; Vincenzo De Sanctis; Saloua M Hmissi; Mohammad A J Abdulla; Yeslem Ekeibed; Omer Ismail; Abdulqadir Nashwan; Dina Soliman; Mohammed Almusharaf; Redwa Hussein
Journal:  Acta Biomed       Date:  2018-04-03
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