Literature DB >> 26696234

A Converter from the Systems Biology Markup Language to the Synthetic Biology Open Language.

Tramy Nguyen, Nicholas Roehner1, Zach Zundel, Chris J Myers.   

Abstract

Standards are important to synthetic biology because they enable exchange and reproducibility of genetic designs. This paper describes a procedure for converting between two standards: the Systems Biology Markup Language (SBML) and the Synthetic Biology Open Language (SBOL). SBML is a standard for behavioral models of biological systems at the molecular level. SBOL describes structural and basic qualitative behavioral aspects of a biological design. Converting SBML to SBOL enables a consistent connection between behavioral and structural information for a biological design. The conversion process described in this paper leverages Systems Biology Ontology (SBO) annotations to enable inference of a designs qualitative function.

Keywords:  SBML; SBOL; genetic design automation; modeling; standards

Mesh:

Year:  2016        PMID: 26696234     DOI: 10.1021/acssynbio.5b00212

Source DB:  PubMed          Journal:  ACS Synth Biol        ISSN: 2161-5063            Impact factor:   5.110


  4 in total

Review 1.  Harmonizing semantic annotations for computational models in biology.

Authors:  Maxwell Lewis Neal; Matthias König; David Nickerson; Göksel Mısırlı; Reza Kalbasi; Andreas Dräger; Koray Atalag; Vijayalakshmi Chelliah; Michael T Cooling; Daniel L Cook; Sharon Crook; Miguel de Alba; Samuel H Friedman; Alan Garny; John H Gennari; Padraig Gleeson; Martin Golebiewski; Michael Hucka; Nick Juty; Chris Myers; Brett G Olivier; Herbert M Sauro; Martin Scharm; Jacky L Snoep; Vasundra Touré; Anil Wipat; Olaf Wolkenhauer; Dagmar Waltemath
Journal:  Brief Bioinform       Date:  2019-03-22       Impact factor: 11.622

2.  A Genetic Circuit Compiler: Generating Combinatorial Genetic Circuits with Web Semantics and Inference.

Authors:  William Waites; Göksel Mısırlı; Matteo Cavaliere; Vincent Danos; Anil Wipat
Journal:  ACS Synth Biol       Date:  2018-11-20       Impact factor: 5.110

Review 3.  Organizing genome engineering for the gigabase scale.

Authors:  Bryan A Bartley; Jacob Beal; Jonathan R Karr; Elizabeth A Strychalski
Journal:  Nat Commun       Date:  2020-02-04       Impact factor: 14.919

4.  Who are the users of synthetic DNA? Using metaphors to activate microorganisms at the center of synthetic biology.

Authors:  Erika Amethyst Szymanski
Journal:  Life Sci Soc Policy       Date:  2018-07-14
  4 in total

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