| Literature DB >> 26696234 |
Tramy Nguyen, Nicholas Roehner1, Zach Zundel, Chris J Myers.
Abstract
Standards are important to synthetic biology because they enable exchange and reproducibility of genetic designs. This paper describes a procedure for converting between two standards: the Systems Biology Markup Language (SBML) and the Synthetic Biology Open Language (SBOL). SBML is a standard for behavioral models of biological systems at the molecular level. SBOL describes structural and basic qualitative behavioral aspects of a biological design. Converting SBML to SBOL enables a consistent connection between behavioral and structural information for a biological design. The conversion process described in this paper leverages Systems Biology Ontology (SBO) annotations to enable inference of a designs qualitative function.Keywords: SBML; SBOL; genetic design automation; modeling; standards
Mesh:
Year: 2016 PMID: 26696234 DOI: 10.1021/acssynbio.5b00212
Source DB: PubMed Journal: ACS Synth Biol ISSN: 2161-5063 Impact factor: 5.110