Literature DB >> 26694542

Macrocyclic Metal Complex-DNA Conjugates for Electrochemical Sensing of Single Nucleobase Changes in DNA.

Jean-Louis H A Duprey1, James Carr-Smith1, Sarah L Horswell1, Jarosław Kowalski2, James H R Tucker1.   

Abstract

The direct incorporation of macrocyclic cyclidene complexes into DNA via automated synthesis results in a new family of metal-functionalized DNA derivatives that readily demonstrate their utility through the ability of one redox-active copper(II)-containing strand to distinguish electrochemically between all four canonical DNA nucleobases at a single site within a target sequence of DNA.

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Year:  2016        PMID: 26694542     DOI: 10.1021/jacs.5b11319

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


  1 in total

1.  Cisplatin adducts of DNA as precursors for nanostructured catalyst materials.

Authors:  Klaudia Englert; Ruba Hendi; Peter H Robbs; Neil V Rees; Alex P G Robinson; James H R Tucker
Journal:  Nanoscale Adv       Date:  2020-08-24
  1 in total

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