OBJECTIVES: New-onset atrial fibrillation (NOAF) during hospitalization is considered a frequent complication associated with worse outcomes in the setting of ST-segment elevation myocardial infarction (STEMI). We aimed to investigate the association of admission serum laboratory parameters, neutrophil to lymphocyte ratio (NLR), and monocyte to high-density lipoprotein ratio (MHR) with NOAF in STEMI patients treated with a primary percutaneous coronary intervention (PCI). PATIENTS AND METHODS: A total of 621 patients who were hospitalized with a diagnosis of STEMI and treated with primary PCI were retrospectively enrolled in the study. NOAF during index hospitalization and overall mortality were reported as the clinical outcomes. RESULTS: In our study population, 40 (6.4%) patients developed NOAF during index hospitalization. Monocyte counts, mean platelet volume (MPV), red cell distribution width (RDW), NLR, MHR, C-reactive protein (CRP), creatinine, glucose, and uric acid levels were higher in the NOAF+ group compared with the NOAF- group. In multivariate regression analysis, age, left-ventricular ejection fraction, left atrial volumes, admission heart rate, multivessel disease, increased levels of CRP, MPV, RDW, uric acid, NLR, and MHR independently predicted NOAF. In addition, NOAF was found to be an independent predictor of overall mortality in the study population. CONCLUSION: For the first time in the literature, admission serum levels of MPV, RDW, uric acid, NLR, and MHR were found to be correlated independently with NOAF after primary PCI.
OBJECTIVES: New-onset atrial fibrillation (NOAF) during hospitalization is considered a frequent complication associated with worse outcomes in the setting of ST-segment elevation myocardial infarction (STEMI). We aimed to investigate the association of admission serum laboratory parameters, neutrophil to lymphocyte ratio (NLR), and monocyte to high-density lipoprotein ratio (MHR) with NOAF in STEMI patients treated with a primary percutaneous coronary intervention (PCI). PATIENTS AND METHODS: A total of 621 patients who were hospitalized with a diagnosis of STEMI and treated with primary PCI were retrospectively enrolled in the study. NOAF during index hospitalization and overall mortality were reported as the clinical outcomes. RESULTS: In our study population, 40 (6.4%) patients developed NOAF during index hospitalization. Monocyte counts, mean platelet volume (MPV), red cell distribution width (RDW), NLR, MHR, C-reactive protein (CRP), creatinine, glucose, and uric acid levels were higher in the NOAF+ group compared with the NOAF- group. In multivariate regression analysis, age, left-ventricular ejection fraction, left atrial volumes, admission heart rate, multivessel disease, increased levels of CRP, MPV, RDW, uric acid, NLR, and MHR independently predicted NOAF. In addition, NOAF was found to be an independent predictor of overall mortality in the study population. CONCLUSION: For the first time in the literature, admission serum levels of MPV, RDW, uric acid, NLR, and MHR were found to be correlated independently with NOAF after primary PCI.
Authors: Maciej R Czerniuk; Zbigniew Bartoszewicz; Iwona Dudzik-Niewiadomska; Tomasz Pilecki; Renata Górska; Krzysztof J Filipiak Journal: Cardiol J Date: 2017-07-17 Impact factor: 2.737
Authors: Manel Ben Halima; Wael Yaakoubi; Selim Boudiche; Bassem Rekik; Fathia Zghal Mghaieth; Sana Ouali; Mohamed Sami Mourali Journal: Tunis Med Date: 2022 fevrier
Authors: Alexander Weymann; Sadeq Ali-Hasan-Al-Saegh; Anton Sabashnikov; Aron-Frederik Popov; Seyed Jalil Mirhosseini; Tong Liu; Mohammadreza Lotfaliani; Michel Pompeu Barros de Oliveira Sá; William L L Baker; Senol Yavuz; Mohamed Zeriouh; Jae-Sik Jang; Hamidreza Dehghan; Lei Meng; Luca Testa; Fabrizio D'Ascenzo; Umberto Benedetto; Gary Tse; Luis Nombela-Franco; Pascal M Dohmen; Abhishek J Deshmukh; Cecilia Linde; Giuseppe Biondi-Zoccai; Gregg W Stone; Hugh Calkins; Integrated Meta-Analysis Of Cardiac Surgery And Cardiology-Group Imcsc-Group Journal: Med Sci Monit Basic Res Date: 2017-05-12
Authors: Alexander Weymann; Sadeq Ali-Hasan-Al-Saegh; Anton Sabashnikov; Aron-Frederik Popov; Seyed Jalil Mirhosseini; Luis Nombela-Franco; Luca Testa; Mohammadreza Lotfaliani; Mohamed Zeriouh; Tong Liu; Hamidreza Dehghan; Senol Yavuz; Michel Pompeu Barros de Oliveira Sá; William L Baker; Jae-Sik Jang; Mengqi Gong; Umberto Benedetto; Pascal M Dohmen; Fabrizio D'Ascenzo; Abhishek J Deshmukh; Giuseppe Biondi-Zoccai; Hugh Calkins; Gregg W Stone; Integrated Meta-Analysis Of Cardiac Surgery And Cardiology-Group Imcsc-Group Journal: Med Sci Monit Basic Res Date: 2017-03-17