Yuehua Zhou1, Jing Zhang2, Yan Zheng2, Qian Liu2, Wenbin Wei2, Ningli Wang2. 1. Beijing Tongren Eye Center, Beijing Ophthalmology & Visual Sciences Key Lab., Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China; Email: yh0220@yahoo. com. 2. Beijing Tongren Eye Center, Beijing Ophthalmology & Visual Sciences Key Lab., Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
Abstract
OBJECTIVE: To evaluate the safety, effectiveness and predictability of allogeneic corneal lens inlays in correcting hyperopia. METHODS: In this case series study. Twenty-one hyperopic patients (37 eyes) received allogeneic corneal lens inlays. The range of preoperative spherical equivalent was 3.25 to 10.00 D, and the mean value was (6.84 ± 2.79)D. All the cases were followed up for 3 months. Uncorrected and best corrected visual acuity and refraction were compared before and after operation. Corneal topography and optical coherence tomography were performed. Ocular response analyzer was used to evaluate the shifts of corneal hysteresis. RESULTS: No intraoperative or postoperative complications were found. Uncorrected distance and near visual acuities (UCDVA and UCNVA) were improved obviously after surgery UCDVA was improved from (4.64 ± 0.25) to (4.89 ± 0.14) (F = 5.919, P < 0.001), and UCNVA was improved from J4.94 to J1.18 (F = 4.926, P < 0.01). The UCNVA in 31 eyes (83.8%) was J1 at 3 months after surgery. Mild overcorrection was the state early after operation, and the refractive power was stable at 1 month after surgery. The average residual spherical equivalent was (-0.63 ± 0.94)D, which was improved significantly from (6.84 ± 2.79)D before surgery. There was no obvious hyperopic regression. The corneal biomechanics did not change before and after surgery. CONCLUSIONS: Allogeneic corneal lens inlays can be used to correct hyperopic eyes with good safety, effectiveness and predictability. It provides a new choice for hyperopic patients.
OBJECTIVE: To evaluate the safety, effectiveness and predictability of allogeneic corneal lens inlays in correcting hyperopia. METHODS: In this case series study. Twenty-one hyperopic patients (37 eyes) received allogeneic corneal lens inlays. The range of preoperative spherical equivalent was 3.25 to 10.00 D, and the mean value was (6.84 ± 2.79)D. All the cases were followed up for 3 months. Uncorrected and best corrected visual acuity and refraction were compared before and after operation. Corneal topography and optical coherence tomography were performed. Ocular response analyzer was used to evaluate the shifts of corneal hysteresis. RESULTS: No intraoperative or postoperative complications were found. Uncorrected distance and near visual acuities (UCDVA and UCNVA) were improved obviously after surgery UCDVA was improved from (4.64 ± 0.25) to (4.89 ± 0.14) (F = 5.919, P < 0.001), and UCNVA was improved from J4.94 to J1.18 (F = 4.926, P < 0.01). The UCNVA in 31 eyes (83.8%) was J1 at 3 months after surgery. Mild overcorrection was the state early after operation, and the refractive power was stable at 1 month after surgery. The average residual spherical equivalent was (-0.63 ± 0.94)D, which was improved significantly from (6.84 ± 2.79)D before surgery. There was no obvious hyperopic regression. The corneal biomechanics did not change before and after surgery. CONCLUSIONS: Allogeneic corneal lens inlays can be used to correct hyperopic eyes with good safety, effectiveness and predictability. It provides a new choice for hyperopic patients.