Literature DB >> 26693597

A new suprasterol by photochemical reaction of 1α,25-dihydroxy-9-methylene-19-norvitamin D3.

Urszula Kulesza1, Lori A Plum2, Hector F DeLuca2, Antonio Mouriño3, Rafal R Sicinski4.   

Abstract

The UV-induced photochemical reaction of 1α,25-dihydroxy-9-methylene-19-norvitamin D3 has been investigated. The pentacyclic structure of the isolated product has been unequivocally established by X-ray crystallographic analysis. The possible reaction paths of the examined photochemical transformation are discussed. Biological in vivo and in vitro tests proved that the photoproduct is devoid of calcemic activity.

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Year:  2016        PMID: 26693597     DOI: 10.1039/c5ob01896j

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  1 in total

1.  Quantitative NMR (qNMR) spectroscopy based investigation of the absolute content, stability and isomerization of 25-hydroxyvitamin D2/D3 and 24(R),25-dihydroxyvitamin D2 in solution phase.

Authors:  Neeraj Singh; Judith Taibon; Stephan Pongratz; Christian Geletneky
Journal:  Sci Rep       Date:  2022-02-22       Impact factor: 4.379

  1 in total

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