Literature DB >> 26692551

Engineering of radiolabeled iron oxide nanoparticles for dual-modality imaging.

Fanrong Ai1,2, Carolina A Ferreira3, Feng Chen2, Weibo Cai2,3,4,5.   

Abstract

Over the last decade, radiolabeled iron oxide nanoparticles have been developed as promising contrast agents for dual-modality positron emission tomography/magnetic resonance imaging (PET/MRI) or single-photon emission computed tomography/magnetic resonance imaging (SPECT/MRI). The combination of PET (or SPECT) with MRI can offer synergistic advantages for noninvasive, sensitive, high-resolution, and quantitative imaging, which is suitable for early detection of various diseases such as cancer. Here, we summarize the recent advances on radiolabeled iron oxide nanoparticles for dual-modality imaging, through the use of a variety of PET (and SPECT) isotopes by using both chelator-based and chelator-free radiolabeling techniques. WIREs Nanomed Nanobiotechnol 2016, 8:619-630. doi: 10.1002/wnan.1386.
© 2015 Wiley Periodicals, Inc.

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Year:  2015        PMID： 26692551      PMCID： PMC4911308          DOI： 10.1002/wnan.1386

Source DB:  PubMed          Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol        ISSN： 1939-0041


  66 in total

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