Nima Kokabi1, Minzhi Xing2, Richard Duszak1, Richard Duszak1, David H Howard3, Kimberly E Applegate1, Juan C Camacho1, Hyun S Kim2,4. 1. Department of Radiology & Imaging Sciences, Emory University School of Medicine, Atlanta, GA 30322, USA. 2. Department of Diagnostic Radiology, Division of Interventional Radiology, Yale University School of Medicine, New Haven, CT 06519, USA. 3. Department of Health Policy & Management, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA. 4. Yale Cancer Center, Yale University, New Haven, CT 06520-8028, USA.
Abstract
AIM: To investigate outcomes in unresectable hepatocellular carcinoma (HCC) patients stratified by sociodemographic and clinical factors in a population study. MATERIALS & METHODS: Surveillance, Epidemiology and End Results (SEER) database was used to identify patients diagnosed in 2000-2011. Overall survival (OS) was stratified using patient sociodemographic characteristics and American Joint Commission on Cancer (AJCC) staging. Log-rank test and Cox proportional hazard models were used to identify prognostic factors of OS. RESULTS: In patients with AJCC stage I and II unresectable HCC, prolonged OS was correlated with being married, younger age, ethnicity, geographic location, living in large urban areas, being insured and higher income and education levels. CONCLUSION: In AJCC stage I and II unresectable HCC patients with favorable sociodemographic factors, prolonged OS maybe in part related to better access to cancer-directed therapy.
AIM: To investigate outcomes in unresectable hepatocellular carcinoma (HCC) patients stratified by sociodemographic and clinical factors in a population study. MATERIALS & METHODS: Surveillance, Epidemiology and End Results (SEER) database was used to identify patients diagnosed in 2000-2011. Overall survival (OS) was stratified using patient sociodemographic characteristics and American Joint Commission on Cancer (AJCC) staging. Log-rank test and Cox proportional hazard models were used to identify prognostic factors of OS. RESULTS: In patients with AJCC stage I and II unresectable HCC, prolonged OS was correlated with being married, younger age, ethnicity, geographic location, living in large urban areas, being insured and higher income and education levels. CONCLUSION: In AJCC stage I and II unresectable HCC patients with favorable sociodemographic factors, prolonged OS maybe in part related to better access to cancer-directed therapy.
Authors: Laura A Evans; Ronald Go; Rahma Warsame; Bharat Nandakumar; Francis K Buadi; Angela Dispenzieri; David Dingli; Martha Q Lacy; Suzanne R Hayman; Prashant Kapoor; Nelson Leung; Amie Fonder; Miriam Hobbs; Yi Lisa Hwa; Eli Muchtar; Taxiarchis V Kourelis; Stephen Russell; John A Lust; Yi Lin; Mustaqeem Siddiqui; Robert A Kyle; Morie A Gertz; S Vincent Rajkumar; Shaji Kumar; Wilson I Gonsalves Journal: Clin Lymphoma Myeloma Leuk Date: 2021-02-17