Literature DB >> 26689921

Complete mesocolic excision: Techniques and outcomes.

Nikoletta Dimitriou1, John Griniatsos1.   

Abstract

Complete mesocolic excision (CME) for the treatment of colon cancer was first introduced in the West in 2008. The first aim of this procedure is to remove the afflicted colon and its accessory lymphovascular supply by resecting the colon and mesocolon in an intact envelope of visceral peritoneum, which holds potentially involved lymph nodes. The second component of CME is a central vascular tie to remove completely all lymph nodes in the central (vertical) direction. In its original iteration, CME was performed via laparotomy, although many centers preferentially perform laparoscopic surgery, with its associated benefits and similar oncological outcomes, as the standard treatment for colonic cancer. Here, we present the surgical techniques for CME in open and laparoscopic surgery, as well as the surgical, pathological and oncological outcomes of the procedure that are available to date. Because there are no randomized control trials comparing CME to "standard" colon surgery, the principles underlying CME seem anatomical and logical, and the results published from the Far East, reporting an 80% 5-year survival rate for Stage III cancer, should guide us.

Entities:  

Keywords:  Colon cancer; Complete mesocolic excision; Laparoscopic colectomy; Laparotomy; Oncological outcome; Surgical technique

Year:  2015        PMID: 26689921      PMCID: PMC4678385          DOI: 10.4251/wjgo.v7.i12.383

Source DB:  PubMed          Journal:  World J Gastrointest Oncol


  38 in total

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Authors:  J Rosenberg; A Fischer; E Haglind
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2.  Laparoscopic lymph node dissection around the inferior mesenteric artery for cancer in the lower sigmoid colon and rectum: is D3 lymph node dissection with preservation of the left colic artery feasible?

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3.  Complete mesocolic excision--a marker of surgical quality?

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Journal:  J Gastrointest Surg       Date:  2009-08-05       Impact factor: 3.452

4.  Complete mesocolic excision with D3 lymph node dissection in laparoscopic colectomy for stages II and III colon cancer: long-term oncologic outcomes in 168 patients.

Authors:  J W Shin; A H Y Amar; S H Kim; J M Kwak; S J Baek; J S Cho; J Kim
Journal:  Tech Coloproctol       Date:  2014-03-15       Impact factor: 3.781

5.  Laparoscopic complete mesocolic excision (CME) with medial access for right-hemi colon cancer: feasibility and technical strategies.

Authors:  Bo Feng; Jing Sun; Tian-Long Ling; Ai-Guo Lu; Ming-Liang Wang; Xue-Yu Chen; Jun-Jun Ma; Jian-Wen Li; Lu Zang; Ding-Pei Han; Min-Hua Zheng
Journal:  Surg Endosc       Date:  2012-06-26       Impact factor: 4.584

6.  Laparoscopic right hemicolectomy with complete mesocolic excision provides acceptable perioperative outcomes but is lengthy--analysis of learning curves for a novice minimally invasive surgeon.

Authors:  George Melich; Duck Hyoun Jeong; Hyuk Hur; Seung Hyuk Baik; Julio Faria; Nam Kyu Kim; Byung Soh Min
Journal:  Can J Surg       Date:  2014-10       Impact factor: 2.089

7.  Disease-free survival after complete mesocolic excision compared with conventional colon cancer surgery: a retrospective, population-based study.

Authors:  Claus Anders Bertelsen; Anders Ulrich Neuenschwander; Jens Erik Jansen; Michael Wilhelmsen; Anders Kirkegaard-Klitbo; Jutaka Reilin Tenma; Birgitte Bols; Peter Ingeholm; Leif Ahrenst Rasmussen; Lars Vedel Jepsen; Else Refsgaard Iversen; Bent Kristensen; Ismail Gögenur
Journal:  Lancet Oncol       Date:  2014-12-31       Impact factor: 41.316

8.  Randomized clinical trial of laparoscopic versus open left colonic resection.

Authors:  M Braga; M Frasson; W Zuliani; A Vignali; N Pecorelli; V Di Carlo
Journal:  Br J Surg       Date:  2010-08       Impact factor: 6.939

9.  Long-term results of laparoscopy-assisted radical right hemicolectomy with D3 lymphadenectomy: clinical analysis with 177 cases.

Authors:  Ding-Pei Han; Ai-Guo Lu; Hao Feng; Pu-Xiong-Zhi Wang; Qi-Feng Cao; Ya-Ping Zong; Bo Feng; Min-Hua Zheng
Journal:  Int J Colorectal Dis       Date:  2012-11-02       Impact factor: 2.571

10.  The mesorectum in rectal cancer surgery--the clue to pelvic recurrence?

Authors:  R J Heald; E M Husband; R D Ryall
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2.  Laparoscopic Versus Open Complete Mesocolon Excision in Right Colon Cancer: A Systematic Review and Meta-Analysis.

Authors:  Mohamed Ali Chaouch; Mohamed Wejih Dougaz; Ibtissem Bouasker; Hichem Jerraya; Wafa Ghariani; Mehdi Khalfallah; Ramzi Nouira; Chadli Dziri
Journal:  World J Surg       Date:  2019-12       Impact factor: 3.352

3.  Extramural venous invasion and depth of extramural invasion on preoperative CT as prognostic imaging biomarkers in patients with locally advanced ascending colon cancer.

Authors:  Jungheum Cho; Young Hoon Kim; Hae Young Kim; Won Chang; Ji Hoon Park
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4.  Colorectal cancer: Surgery for colorectal cancer - standardization required.

Authors:  J Calvin Coffey; Peter Dockery
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2016-03-09       Impact factor: 46.802

Review 5.  Complete mesocolic excision versus conventional hemicolectomy in patients with right colon cancer: a systematic review and meta-analysis.

Authors:  Ottavia De Simoni; Andrea Barina; Antonio Sommariva; Marco Tonello; Mario Gruppo; Genny Mattara; Antonio Toniato; Pierluigi Pilati; Boris Franzato
Journal:  Int J Colorectal Dis       Date:  2020-11-10       Impact factor: 2.571

6.  Surgical treatment and survival from colorectal cancer in Denmark, England, Norway, and Sweden: a population-based study.

Authors:  Sara Benitez Majano; Chiara Di Girolamo; Bernard Rachet; Camille Maringe; Marianne Grønlie Guren; Bengt Glimelius; Lene Hjerrild Iversen; Edrun Andrea Schnell; Kristina Lundqvist; Jane Christensen; Melanie Morris; Michel P Coleman; Sarah Walters
Journal:  Lancet Oncol       Date:  2018-12-10       Impact factor: 41.316

7.  Adjuvant chemotherapy in stage II-III operated colon cancer patients from a nontrial cohort in a low colon cancer prevalence country with predominant use of modified CAPOX.

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Journal:  South Asian J Cancer       Date:  2019 Jul-Sep

8.  Feasibility and Safety of Laparoscopic Radical Colectomy for T4b Colon Cancer at a University Hospital in Vietnam.

Authors:  Thinh H Nguyen; Hung X Tran; Truc T Thai; Duc M La; Huy D Tran; Kien T Le; Vinh T N Pham; An N T Le; Bac H Nguyen
Journal:  Biomed Res Int       Date:  2020-11-11       Impact factor: 3.411

9.  Development and evaluation of a Japanese prediction model for low anterior resection syndrome after rectal cancer surgery.

Authors:  Masakatsu Paku; Norikatsu Miyoshi; Shiki Fujino; Tsuyoshi Hata; Takayuki Ogino; Hidekazu Takahashi; Mamoru Uemura; Tsunekazu Mizushima; Hirofumi Yamamoto; Yuichiro Doki; Hidetoshi Eguchi
Journal:  BMC Gastroenterol       Date:  2022-05-13       Impact factor: 3.067

Review 10.  Right colic artery anatomy: a systematic review of cadaveric studies.

Authors:  M Haywood; C Molyneux; V Mahadevan; N Srinivasaiah
Journal:  Tech Coloproctol       Date:  2017-12-02       Impact factor: 3.781

  10 in total

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