Literature DB >> 26689396

The Impact of Obesity on the Outcome of Decompression Surgery in Degenerative Lumbar Spinal Canal Stenosis: Analysis of the Lumbar Spinal Outcome Study (LSOS): A Swiss Prospective Multicenter Cohort Study.

Jakob M Burgstaller1, Ulrike Held, Florian Brunner, François Porchet, Mazda Farshad, Johann Steurer, Nils H Ulrich.   

Abstract

STUDY
DESIGN: Prospective, multicenter cohort study including 8 medical centers of the Cantons Zurich, Lucerne, and Thurgau, Switzerland.
OBJECTIVE: The aim of the study was to assess whether obese patients benefit after decompression surgery for degenerative lumbar spinal stenosis (DLSS). SUMMARY AND BACKGROUND DATA: Lumbar decompression surgery has been shown to improve quality of life in patients with DLSS. In the existing literature, the efficacy of lumbar decompression in the obese population remains controversial.
METHODS: Baseline patient characteristics and outcomes were analyzed at 6 and 12 months follow-up with the Spinal Stenosis Measure (SSM), the Numeric Rating Scale (NRS), Feeling Thermometer (FT), the EQ-5D-EL, and the Roland and Morris Disability Questionnaire (RMDQ). Body mass index (BMI) was classified into 3 categories according to the WHO. Minimal clinically important differences (MCIDs) in SSM for different BMI categories were considered as main outcome.
RESULTS: Of the 656 patients in the Lumbar Spinal Outcome Study database as of end of October 2014, 166 patients met the inclusion criteria. Fifty (30.1%) had a BMI less than 25 (underweight and normal weight group), 72 (43.4%) had a BMI between 25 and less than 30 (preobesity group), and 44 (26.5%) patients had a BMI at least 30 (obese group). We found for the main outcome that in obese patients 36% reached MCID at 6 months, and 48% at 12 months. The estimated odds ratios for MCID in the obese group were 0.78 (0.34-1.82) at 6 months and 0.99 (0.44-2.23) at 12 months in a logistic regression model adjusting for levels of laminectomy. In the additional outcomes, SSM, NRS, FT, and RMDQ showed statistically significant mean improvements in the 6 and 12 months follow-up.
CONCLUSION: Obese patients can expect clinical improvement after lumbar decompression for DLSS, but the percentage of patients with a meaningful improvement is lower than in the group of patients with underweight, normal weight, and preobese weight at 6 and 12 months.

Entities:  

Mesh:

Year:  2016        PMID: 26689396     DOI: 10.1097/BRS.0000000000001128

Source DB:  PubMed          Journal:  Spine (Phila Pa 1976)        ISSN: 0362-2436            Impact factor:   3.468


  10 in total

1.  Cost-effectiveness of conservative versus surgical treatment strategies of lumbar spinal stenosis in the Swiss setting: analysis of the prospective multicenter Lumbar Stenosis Outcome Study (LSOS).

Authors:  A Aichmair; J M Burgstaller; M Schwenkglenks; J Steurer; F Porchet; F Brunner; M Farshad
Journal:  Eur Spine J       Date:  2016-12-31       Impact factor: 3.134

2.  A novel use of the Spine Tango registry to evaluate selection bias in patient recruitment into clinical studies: an analysis of patients participating in the Lumbar Spinal Stenosis Outcome Study (LSOS).

Authors:  H-J Becker; S Nauer; F Porchet; F S Kleinstück; D Haschtmann; T F Fekete; J Steurer; A F Mannion
Journal:  Eur Spine J       Date:  2016-11-14       Impact factor: 3.134

3.  Effect of BMI on the clinical outcome following microsurgical decompression in over-the-top technique: bi-centric study with an analysis of 744 patients.

Authors:  Tamara Herold; Ralph Kothe; Christoph J Siepe; Oliver Heese; Wolfgang Hitzl; Andreas Korge; Karin Wuertz-Kozak
Journal:  Eur Spine J       Date:  2021-02-27       Impact factor: 3.134

4.  Associations between Obesity and Spinal Diseases: A Medical Expenditure Panel Study Analysis.

Authors:  Binwu Sheng; Chaoling Feng; Donglan Zhang; Hugh Spitler; Lu Shi
Journal:  Int J Environ Res Public Health       Date:  2017-02-13       Impact factor: 3.390

Review 5.  The influence of comorbidities on the treatment outcome in symptomatic lumbar spinal stenosis: A systematic review and meta-analysis.

Authors:  Amandine Bays; Andrea Stieger; Ulrike Held; Lisa J Hofer; Eva Rasmussen-Barr; Florian Brunner; Johann Steurer; Maria M Wertli
Journal:  N Am Spine Soc J       Date:  2021-06-02

6.  Effect of body mass index on surgical times of lumbar laminoplasty and lower limb arthroplasties.

Authors:  Kengo Harato; Mitsuru Yagi; Nobuyuki Fujita; Shu Kobayashi; Akihito Ohya; Kazuya Kaneda; Yu Iwama; Masaya Nakamura; Morio Matsumoto
Journal:  BMC Musculoskelet Disord       Date:  2019-09-06       Impact factor: 2.362

7.  Factors influencing harmonized health data collection, sharing and linkage in Denmark and Switzerland: A systematic review.

Authors:  Lester Darryl Geneviève; Andrea Martani; Maria Christina Mallet; Tenzin Wangmo; Bernice Simone Elger
Journal:  PLoS One       Date:  2019-12-12       Impact factor: 3.240

8.  Effects of calcitonin addition on epidural injection in patients with degenerative spinal canal stenosis: a randomized double blind clinical trial.

Authors:  Poupak Rahimzadeh; Seyed Mani Mahdavi; Kamran Mahmoudi; Hassan Ghandhari; Ali Babashahi; Parvaneh Zandi; Seyed Hamid Reza Faiz
Journal:  Turk J Anaesthesiol Reanim       Date:  2021-12

9.  Early Failures After Lumbar Discectomy Surgery: An Analysis of 62 690 Patients.

Authors:  Andre M Samuel; Kyle Morse; Francis Lovecchio; Noor Maza; Avani S Vaishnav; Yoshihiro Katsuura; Sravisht Iyer; Steven J McAnany; Todd J Albert; Catherine Himo Gang; Sheeraz A Qureshi
Journal:  Global Spine J       Date:  2020-07-17

10.  Obesity and Spine Surgery: A Qualitative Review About Outcomes and Complications. Is It Time for New Perspectives on Future Researches?

Authors:  Fabio Cofano; Giuseppe Di Perna; Daria Bongiovanni; Vittoria Roscigno; Bianca Maria Baldassarre; Salvatore Petrone; Fulvio Tartara; Diego Garbossa; Marco Bozzaro
Journal:  Global Spine J       Date:  2021-06-15
  10 in total

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