Literature DB >> 26689121

Receptor Crosslinking in Drug Delivery: Detour to the Lysosome?

Manfred Ogris1, Haider Sami1.   

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Year:  2015        PMID: 26689121      PMCID: PMC4700121          DOI: 10.1038/mt.2015.207

Source DB:  PubMed          Journal:  Mol Ther        ISSN: 1525-0016            Impact factor:   11.454


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  18 in total

1.  Disconnecting the yin and yang relation of epidermal growth factor receptor (EGFR)-mediated delivery: a fully synthetic, EGFR-targeted gene transfer system avoiding receptor activation.

Authors:  A Schäfer; A Pahnke; D Schaffert; W M van Weerden; C M A de Ridder; W Rödl; A Vetter; C Spitzweg; R Kraaij; E Wagner; Manfred Ogris
Journal:  Hum Gene Ther       Date:  2011-08-10       Impact factor: 5.695

2.  Inhibition of endosomal/lysosomal degradation increases the infectivity of human immunodeficiency virus.

Authors:  Brenda L Fredericksen; Bangdong L Wei; Jian Yao; Tianci Luo; J Victor Garcia
Journal:  J Virol       Date:  2002-11       Impact factor: 5.103

3.  Tuning nanoparticle uptake: live-cell imaging reveals two distinct endocytosis mechanisms mediated by natural and artificial EGFR targeting ligand.

Authors:  Frauke M Mickler; Leonhard Möckl; Nadia Ruthardt; Manfred Ogris; Ernst Wagner; Christoph Bräuchle
Journal:  Nano Lett       Date:  2012-06-05       Impact factor: 11.189

4.  Epidermal growth factor receptor-targeted (131)I-therapy of liver cancer following systemic delivery of the sodium iodide symporter gene.

Authors:  Kathrin Klutz; David Schaffert; Michael J Willhauck; Geoffrey K Grünwald; Rudolf Haase; Nathalie Wunderlich; Christian Zach; Franz J Gildehaus; Reingard Senekowitsch-Schmidtke; Burkhard Göke; Ernst Wagner; Manfred Ogris; Christine Spitzweg
Journal:  Mol Ther       Date:  2011-01-18       Impact factor: 11.454

5.  Transferrin-polycation-mediated introduction of DNA into human leukemic cells: stimulation by agents that affect the survival of transfected DNA or modulate transferrin receptor levels.

Authors:  M Cotten; F Längle-Rouault; H Kirlappos; E Wagner; K Mechtler; M Zenke; H Beug; M L Birnstiel
Journal:  Proc Natl Acad Sci U S A       Date:  1990-06       Impact factor: 11.205

6.  Cetuximab retargeting of adenovirus via the epidermal growth factor receptor for treatment of intraperitoneal ovarian cancer.

Authors:  Joanne Morrison; Simon S Briggs; Nicola K Green; Clemens Thoma; Kerry D Fisher; Sean Kehoe; Leonard W Seymour
Journal:  Hum Gene Ther       Date:  2009-03       Impact factor: 5.695

7.  Specific antibody-receptor interactions trigger InlAB-independent uptake of Listeria monocytogenes into tumor cell lines.

Authors:  Martin Heisig; Alexa Frentzen; Birgit Bergmann; Katharina Galmbacher; Ivaylo Gentschev; Christian Hotz; Christoph Schoen; Jochen Stritzker; Joachim Fensterle; Ulf R Rapp; Werner Goebel
Journal:  BMC Microbiol       Date:  2011-07-11       Impact factor: 3.605

8.  Trastuzumab: updated mechanisms of action and resistance in breast cancer.

Authors:  Thuy Vu; Francois X Claret
Journal:  Front Oncol       Date:  2012-06-18       Impact factor: 6.244

Review 9.  EGF receptor trafficking: consequences for signaling and cancer.

Authors:  Alejandra Tomas; Clare E Futter; Emily R Eden
Journal:  Trends Cell Biol       Date:  2013-11-29       Impact factor: 20.808

10.  Receptor Crosslinking: A General Method to Trigger Internalization and Lysosomal Targeting of Therapeutic Receptor:Ligand Complexes.

Authors:  Paul R Moody; Edward J Sayers; Johannes P Magnusson; Cameron Alexander; Paola Borri; Peter Watson; Arwyn T Jones
Journal:  Mol Ther       Date:  2015-09-28       Impact factor: 11.454

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  1 in total

1.  Nanomedicines for the Delivery of Biologics.

Authors:  John Wahlich; Arpan Desai; Francesca Greco; Kathryn Hill; Arwyn T Jones; Randall J Mrsny; Gianfranco Pasut; Yvonne Perrie; F Philipp Seib; Leonard W Seymour; Ijeoma F Uchegbu
Journal:  Pharmaceutics       Date:  2019-05-03       Impact factor: 6.321

  1 in total

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