Harshal A Lahoti1, Bal Krishna Goyal2. 1. Senior Resident, Department of Cardiology, Bombay Hospital Institute of Medical Sciences, Bombay Hospital, 12, New Marine Lines, Mumbai 400020, India. Electronic address: harshal_dr@yahoo.com. 2. Director, Interventional Cardiology and Hon. Dean, Bombay Hospital Institute of Medical Sciences, Bombay Hospital, 12, New Marine Lines, Mumbai 400020, India.
Abstract
INTRODUCTION: Tenecteplase can be a more effective and convenient alternative in treatment of prosthetic valve thrombosis (PVT). CASE: We hereby present a case of the use of Tenecteplase for recurrence of mitral valve thrombosis in a patient who was brought as an emergency with breathing difficulty at rest. A single intravenous bolus of Tenecteplase relieved her symptoms dramatically within a few hours. This is in contradistinction to her earlier similar presentation with valve thrombosis a year back, when both streptokinase and urokinase had not worked. CONCLUSION: The use of Tenecteplase in PVT is reasonable, but needs more documentation. The therapeutic response was remarkable in our case. It is also better suited for recurrence of valve thrombosis as streptokinase cannot be used for a second time.
INTRODUCTION: Tenecteplase can be a more effective and convenient alternative in treatment of prosthetic valve thrombosis (PVT). CASE: We hereby present a case of the use of Tenecteplase for recurrence of mitral valve thrombosis in a patient who was brought as an emergency with breathing difficulty at rest. A single intravenous bolus of Tenecteplase relieved her symptoms dramatically within a few hours. This is in contradistinction to her earlier similar presentation with valve thrombosis a year back, when both streptokinase and urokinase had not worked. CONCLUSION: The use of Tenecteplase in PVT is reasonable, but needs more documentation. The therapeutic response was remarkable in our case. It is also better suited for recurrence of valve thrombosis as streptokinase cannot be used for a second time.
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