Literature DB >> 26687559

Leucocontextins A-R, lanostane-type triterpenoids from Ganoderma leucocontextum.

Zhen-Zhu Zhao1, He-Ping Chen1, Zheng-Hui Li2, Ze-Jun Dong3, Xue Bai3, Zhong-Yu Zhou4, Tao Feng5, Ji-Kai Liu6.   

Abstract

Eighteen new lanostane-type triterpenoids, namely leucocontextins A-R (1-18) were isolated from the fruiting bodies of Ganoderma leucocontextum. Their structures were established by 1D and 2D NMR data in conjunction with HRESIMS/HREIMS, X-ray single crystal diffraction analysis. Compound 18 exhibited weak cytotoxicity against K562 and MCF-7 cell lines with IC50 of 20-30 μM.
Copyright © 2015 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Cytotoxicity; Ganoderma leucocontextum; Triterpenoids

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Year:  2015        PMID： 26687559     DOI： 10.1016/j.fitote.2015.12.004

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  3 in total

1.  Ganoderiol F purified from Ganoderma leucocontextum retards cell cycle progression by inhibiting CDK4/CDK6.

Authors:  Xiangmin Li; Yizhen Xie; Juanjuan Peng; Huiping Hu; Qingping Wu; Burton B Yang
Journal:  Cell Cycle       Date:  2019-09-22       Impact factor: 4.534

2.  Lanostane Triterpenoids from Fruiting Bodies of Ganoderma leucocontextum.

Authors:  Zhen-Zhu Zhao; He-Ping Chen; Ying Huang; Zheng-Hui Li; Ling Zhang; Tao Feng; Ji-Kai Liu
Journal:  Nat Prod Bioprospect       Date:  2016-02-12

3.  Whole-genome assembly of Ganoderma leucocontextum (Ganodermataceae, Fungi) discovered from the Tibetan Plateau of China.

Authors:  Yuanchao Liu; Longhua Huang; Huiping Hu; Manjun Cai; Xiaowei Liang; Xiangmin Li; Zhi Zhang; Yizhen Xie; Chun Xiao; Shaodan Chen; Diling Chen; Tianqiao Yong; Honghui Pan; Xiong Gao; Qingping Wu
Journal:  G3 (Bethesda)       Date:  2021-12-08       Impact factor: 3.154
  3 in total

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