Jonathan W Shum1, Ioannis Chatzistefanou2, Mohammed Qaisi3, Joshua E Lubek4, Robert A Ord5. 1. Assistant Professor, Department of Oral and Maxillofacial Surgery, University of Texas Health Science Center, Houston, TX, USA. Electronic address: Jonathan.shum@uth.tmc.edu. 2. Assistant Professor, Department of Oral and Maxillofacial Surgery, Aristotle University of Thessaloniki, Greece. 3. Assistant Professor, Department of Oral and Maxillofacial Surgery, University of Mississippi, Jackson, MS, USA. 4. Assistant Professor and Fellowship Director Oral, Head and Neck Surgery/Microvascular Surgery, Department of Oral and Maxillofacial Surgery, University of Maryland School of Dentistry and Greenebaum Cancer Center, Baltimore, MD, USA. 5. Professor and Chair, Department of Oral and Maxillofacial Surgery, University of Maryland School of Dentistry and Greenebaum Cancer Center, Baltimore, MD, USA.
Abstract
OBJECTIVE: Approximately 78% of minor salivary gland tumors are malignant, of which adenoid cystic carcinoma (ACC) represents 15% in our series. ACC is an uncommon tumor characterized by slow growth and a high potential for recurrence. This series of 29 consecutive patients examines clincopathologic features, management, and survival outcomes. MATERIALS AND METHODS: This study is a retrospective chart review of 29 patients with ACC of the minor salivary glands in a period of 23 years (1989 and 2012). RESULTS: The mean age was 61.2 years (16-89 years), with no gender predilection. The majority occurred in the palate/maxilla (66%) and initial presentation was stage IV. Mean follow-up was 42.6 months. Recurrence rate was 10% local, 14% distant over the observation period. CONCLUSIONS: The palate/maxilla is the preferred location for occurrence, and initial presentation at stage IV is common. Postoperative radiation remains a common strategy to prevent local recurrence in lesions with adverse features.
OBJECTIVE: Approximately 78% of minor salivary gland tumors are malignant, of which adenoid cystic carcinoma (ACC) represents 15% in our series. ACC is an uncommon tumor characterized by slow growth and a high potential for recurrence. This series of 29 consecutive patients examines clincopathologic features, management, and survival outcomes. MATERIALS AND METHODS: This study is a retrospective chart review of 29 patients with ACC of the minor salivary glands in a period of 23 years (1989 and 2012). RESULTS: The mean age was 61.2 years (16-89 years), with no gender predilection. The majority occurred in the palate/maxilla (66%) and initial presentation was stage IV. Mean follow-up was 42.6 months. Recurrence rate was 10% local, 14% distant over the observation period. CONCLUSIONS: The palate/maxilla is the preferred location for occurrence, and initial presentation at stage IV is common. Postoperative radiation remains a common strategy to prevent local recurrence in lesions with adverse features.
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