Literature DB >> 26684627

Evaluation of an oral appliance in patients with mild to moderate obstructive sleep apnea syndrome intolerant to continuous positive airway pressure use: Preliminary results.

S Cantore1, A Ballini2, D Farronato3, G Malcangi4, G Dipalma4, F Assandri5, U Garagiola5, F Inchingolo4, D De Vito1, N Cirulli1.   

Abstract

Obstructive sleep apnea syndrome (OSAS) is a phenomenon of repeated, episodic reduction, or cessation of airflow (hypopnea/apnea) as a result of upper airways obstruction. First-line treatment in younger children is adenotonsillectomy, although other available treatment options in middle-aged adults include continuous positive airways pressure (CPAP) and airway adjuncts. Oral appliances (OA) are a viable treatment alternative in patients with OSAS.The objective of this study was to assess, in a 1-year follow-up study, an OA in OSAS patients. The participants were subjected to polysomnographic examination with a validated device (MicroMESAM). Eight participants were fitted with a Thornton Adjustable Positioner (TAP). The participants were asked to wear the test appliance for 7 nights, and in case of compliance, for 6 months. The selected patients record their usage of the appliance and any adverse effects in a treatment journal. The research focused on the following outcomes: sleep apnea (i.e. reduction in the apnea/hypopnea index) and the effect of oral appliances on daytime function.In conclusion, the results suggest that OA have a definite role in the treatment of snoring and sleep apnea.
© The Author(s) 2015.

Entities:  

Keywords:  Thornton Adjustable Positioner; apnea-hypopnea index; continuous positive airway pressure; obstructive sleep apnea syndrome; oral appliance

Mesh:

Year:  2015        PMID: 26684627      PMCID: PMC5806714          DOI: 10.1177/0394632015590949

Source DB:  PubMed          Journal:  Int J Immunopathol Pharmacol        ISSN: 0394-6320            Impact factor:   3.219


  25 in total

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Authors:  D J Gale; R H Sawyer; A Woodcock; P Stone; R Thompson; K O'Brien
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2.  Growth of the nasopharynx and adenoid development from one to eighteeen years.

Authors:  C S Handelman; G Osborne
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3.  A randomized prospective long-term study of two oral appliances for sleep apnoea treatment.

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4.  Reversal of obstructive sleep apnoea by continuous positive airway pressure applied through the nares.

Authors:  C E Sullivan; F G Issa; M Berthon-Jones; L Eves
Journal:  Lancet       Date:  1981-04-18       Impact factor: 79.321

Review 5.  Oral appliances for snoring and obstructive sleep apnea: a review.

Authors:  Kathleen A Ferguson; Rosalind Cartwright; Robert Rogers; Wolfgang Schmidt-Nowara
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6.  Practice parameters for the treatment of snoring and Obstructive Sleep Apnea with oral appliances: an update for 2005.

Authors:  Clete A Kushida; Timothy I Morgenthaler; Michael R Littner; Cathy A Alessi; Dennis Bailey; Jack Coleman; Leah Friedman; Max Hirshkowitz; Sheldon Kapen; Milton Kramer; Teofilo Lee-Chiong; Judith Owens; Jeffrey P Pancer
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Authors:  Carole L Marcus; Lee Jay Brooks; Kari A Draper; David Gozal; Ann Carol Halbower; Jacqueline Jones; Michael S Schechter; Sally Davidson Ward; Stephen Howard Sheldon; Richard N Shiffman; Christopher Lehmann; Karen Spruyt
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Review 8.  Does this patient have obstructive sleep apnea?: The Rational Clinical Examination systematic review.

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Review 9.  Oral appliance treatment for obstructive sleep apnea: an update.

Authors:  Kate Sutherland; Olivier M Vanderveken; Hiroko Tsuda; Marie Marklund; Frederic Gagnadoux; Clete A Kushida; Peter A Cistulli
Journal:  J Clin Sleep Med       Date:  2014-02-15       Impact factor: 4.062

Review 10.  Improvements in current treatments and emerging therapies for adult obstructive sleep apnea.

Authors:  Neil Freedman
Journal:  F1000Prime Rep       Date:  2014-05-06
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4.  Patients with Obstructive Sleep Apnea Have Altered Levels of Four Cytokines Associated with Cardiovascular and Kidney Disease, but Near Normal Levels with Airways Therapy.

Authors:  Ye Wang; Richard B Meagher; Suresh Ambati; Huimin Cheng; Ping Ma; Bradley G Phillips
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