Literature DB >> 26683670

Correction: Do Longer Intervals between Challenges Reduce the Risk of Adverse Reactions in Oral Wheat Challenges?

Noriyuki Yanagida, Takanori Imai, Sakura Sato, Motohiro Ebisawa.   

Abstract

Entities:  

Year:  2015        PMID: 26683670      PMCID: PMC4684278          DOI: 10.1371/journal.pone.0145567

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


× No keyword cloud information.
There are errors in Table 1. Please see the corrected Table 1 here.
Table 1

Grading of symptoms.

1 (mild)2 (moderate)3 (severe)
SkinLocalized urticarial or exanthema or wheal or pruritisGeneralized urticarial or exanthema or wheal or pruritis-
Swollen eyelid or lipSwollen face-
Gastrointestinal tractPruritus of the throat or oral cavityThroat pain-
Mild abdominal painModerate abdominal painCramps
Nausea, emesis, diarrheaRecurrent emesis or diarrheaContinuous emesis, loss of bowel control
Respiratory tractIntermittent cough, nasal congestion, sneezing, rhinorrheaRepetitive coughPersistent cough, hoarseness, “barky” cough
-Chest tightness, mild wheezingApparent wheezing, dyspnea, cyanosis, saturation <92%, swallowing or speaking difficulties, throat tightness, respiratory arrest
Cardiovascular-Pale face, mild hypotension, tachycardia (increase >15 beats/min)Hypotension, dysrhythmia, severe bradycardia, cardiac arrest
NeurologicalChange in activity level, tiredness“Light-headedness,” feeling of “pending doom,” somnolenceConfusion, loss of consciousness, incontinence

The severity score should be based on the organ system most affected.

Hypotension was defined as systolic blood pressure of <70 mmHg (ages, 1 month to 1 year), <(70 mmHg + [2 × age]) (ages, 1–10 years), and <90 mmHg (>11 years).

Mild hypotension was defined as systolic blood pressure of <80 mmHg (ages, 1 month to 1 year), <(80 mmHg + [2 × age]) (ages, 1–10 years), and <100 mmHg (>11 years).

Total severity scores were defined as the grade of cardiovascular symptoms + the grade of respiratory symptoms + the maximum grade of other symptoms.

The severity score should be based on the organ system most affected. Hypotension was defined as systolic blood pressure of <70 mmHg (ages, 1 month to 1 year), <(70 mmHg + [2 × age]) (ages, 1–10 years), and <90 mmHg (>11 years). Mild hypotension was defined as systolic blood pressure of <80 mmHg (ages, 1 month to 1 year), <(80 mmHg + [2 × age]) (ages, 1–10 years), and <100 mmHg (>11 years). Total severity scores were defined as the grade of cardiovascular symptoms + the grade of respiratory symptoms + the maximum grade of other symptoms.
  1 in total

1.  Do Longer Intervals between Challenges Reduce the Risk of Adverse Reactions in Oral Wheat Challenges?

Authors:  Noriyuki Yanagida; Takanori Imai; Sakura Sato; Motohiro Ebisawa
Journal:  PLoS One       Date:  2015-12-01       Impact factor: 3.240

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.