| Literature DB >> 2668317 |
G R Pietroboni1, G B Harnett, M R Bucens.
Abstract
The effect of centrifugal inoculation of human immunodeficiency virus (HIV) and human herpesvirus-6 (HHV-6) on the infectivity of the viruses for cell cultures was examined. Three HIV-1 strains, ARV-2, HTLV-IIIb and a local isolate, WA-46c, were tested in peripheral blood lymphocytes, HUT-78, H9 and MT-2 cells. The HHV-6 strain was a local isolate and was studied only in peripheral blood lymphocyte cultures. Centrifugal inoculation of the viruses at a force of 2500 x g for 60 min, enhanced HIV-1 infectivity by a factor of about 10-fold in all cell cultures tested. Infectivity was increased about 100-fold for HHV-6.Entities:
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Year: 1989 PMID: 2668317 DOI: 10.1016/0166-0934(89)90010-4
Source DB: PubMed Journal: J Virol Methods ISSN: 0166-0934 Impact factor: 2.014