Literature DB >> 26681574

Autonomic dysfunction elicited by a medulla oblongata injury after fourth ventricle tumor surgery in a pediatric patient.

A Martín-Gallego1, I Andrade-Andrade2, M S Dawid-Milner2, M Domínguez-Páez3, L Romero-Moreno3, L González-García3, A Carrasco-Brenes3, M Segura-Fernández-Nogueras3, B Ros-López3, M A Arráez-Sánchez3.   

Abstract

We report the case of a 9-year-old male patient with a recurrent fourth ventricle anaplastic ependymoma who developed severe arterial hypertension and blood pressure lability during and after surgery. A punctual bilateral lesion located within mid dorsal medulla oblongata caused by both infiltration and surgical resection was observed in postoperative MRI. Three years later, the patient remained neurologically stable but the family referred the presence of a chronic tachycardia as well as palpitations and sweating with flushing episodes related to environmental stress. On autonomic evaluation, an increase in sympathetic outflow with tachycardia together with orthostatic hypotension caused by baroreceptor reflex dysfunction was observed. We postulate that a bilateral injury to both nuclei of the solitary tract may have caused central dysautonomia.
Copyright © 2015 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Autonomic nervous system; Brainstem; Dysautonomia; Fourth ventricle; Medulla oblongata; Nucleus of the solitary tract; Pediatric

Mesh:

Year:  2015        PMID: 26681574     DOI: 10.1016/j.autneu.2015.12.002

Source DB:  PubMed          Journal:  Auton Neurosci        ISSN: 1566-0702            Impact factor:   3.145


  2 in total

1.  Cardiovascular autonomic responses in patients with Parkinson disease to pedunculopontine deep brain stimulation.

Authors:  Jonathan A Hyam; Holly A Roy; Yongzhi Huang; Sean Martin; Shouyan Wang; Jodi Rippey; Terry J Coyne; Ian Stewart; Graham Kerr; Peter Silburn; David J Paterson; Tipu Z Aziz; Alexander L Green
Journal:  Clin Auton Res       Date:  2019-09-06       Impact factor: 4.435

2.  Conservative rehabilitation for a patient presenting with severe orthostatic hypotension after surgical management of brainstem tumor: illustrative case.

Authors:  Misato Nagumo; Syoichi Tashiro; Nanako Hijikata; Aiko Ishikawa; Takenori Akiyama; Tetsuya Tsuji
Journal:  J Neurosurg Case Lessons       Date:  2021-06-21
  2 in total

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