Literature DB >> 26679890

The Effect of Local Intraoperative Steroid Administration on the Rate of Postoperative Dysphagia Following ACDF: A Study of 245,754 Patients.

Jourdan M Cancienne1, Brian C Werner, Alex E Loeb, Scott S Yang, Hamid Hassanzadeh, Anuj Singla, Frank H Shen, Adam L Shimer.   

Abstract

STUDY
DESIGN: A retrospective database analysis.
OBJECTIVE: The aim of this study is to compare rates of postoperative dysphagia, length of stay, infection, and wound complications following short and long anterior cervical discectomy and fusion (ACDF) in patients who received local intraoperative steroids and those who did not. SUMMARY OF BACKGROUND DATA: Only one prior small institutional study has investigated the application of local steroids at the time of ACDF to decrease postoperative dysphagia.
METHODS: A large administrative database was utilized to compare rates of postoperative dysphagia, length of stay, and infectious complications within 90 days in patients who received local steroid following short (1-2 level) and long (3 or more level) ACDF and control groups who did not. Nonobtainable information within the database included type of steroid, application technique, outcome data, and incidence of miscoding and noncoding by physicians. Odds ratios (ORs), 95% confidence intervals (95% CIs) and P values were then calculated using SPSS.
RESULTS: The incidence of dysphagia was significantly lower (9.0% vs. 14.6%, P = 0.005) in patients who received local steroid in the long ACDF group (n = 322) than a control group who did not (n = 45,432). This was not observed (P = 0.198) in the short ACDF group who received steroid (n = 1770) compared with a control group who did not (n = 198,230). The mean difference in length of stay was 1 day less for patients who received local steroid in both the short and long ACDF groups (P < 0.0001). The combined rate of postoperative infection and wound complications was not significantly different between steroid and control groups (P = 0.717).
CONCLUSION: This analysis of a large administrative database suggests that local intraoperative steroid is associated with a significantly reduced rate of postoperative dysphagia after long ACDF and reduced average length of stay following both long and short ACDF without any increase in the rate of postoperative infection or wound complication. LEVEL OF EVIDENCE: 3.

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Year:  2016        PMID: 26679890     DOI: 10.1097/BRS.0000000000001407

Source DB:  PubMed          Journal:  Spine (Phila Pa 1976)        ISSN: 0362-2436            Impact factor:   3.468


  7 in total

1.  The Effects of Perioperative Corticosteroids on Dysphagia Following Surgical Procedures Involving the Anterior Cervical Spine: A Prospective, Randomized, Controlled, Double-Blinded Clinical Trial.

Authors:  Shari Cui; Scott D Daffner; John C France; Sanford E Emery
Journal:  J Bone Joint Surg Am       Date:  2019-11-20       Impact factor: 5.284

2.  Effect of perioperative steroids on dysphagia after anterior cervical spine surgery: A systematic review.

Authors:  Abidemi S Adenikinju; Sameer H Halani; Rima S Rindler; Matthew F Gary; Keith W Michael; Faiz U Ahmad
Journal:  Int J Spine Surg       Date:  2017-03-06

Review 3.  Insights Into Oropharyngeal Dysphagia From Administrative Data and Clinical Registries: A Literature Review.

Authors:  Rebecca S Bartlett; Susan L Thibeault
Journal:  Am J Speech Lang Pathol       Date:  2018-05-03       Impact factor: 2.408

4.  Key perspectives on Woven EndoBridge device for wide-necked bifurcation aneurysms, endoscopic endonasal clipping of intracranial aneurysms, retrosigmoid versus translabyrinthine approaches for acoustic neuromas, and impact of local intraoperative steroid administration on postoperative dysphagia following anterior cervical discectomy and fusion.

Authors:  Visish M Srinivasan; Peter Kan; Anand V Germanwala; Panayiotis Pelargos; Angela Bohnen; Winward Choy; Isaac Yang; Zachary A Smith
Journal:  Surg Neurol Int       Date:  2016-10-07

Review 5.  Corticosteroid Administration to Prevent Complications of Anterior Cervical Spine Fusion: A Systematic Review.

Authors:  Shayan Abdollah Zadegan; Seyed Behnam Jazayeri; Aidin Abedi; Hirbod Nasiri Bonaki; Alexander R Vaccaro; Vafa Rahimi-Movaghar
Journal:  Global Spine J       Date:  2017-06-23

6.  The effect of local steroid application on bony fusion in a rat posterolateral spinal arthrodesis model.

Authors:  Abhishek Kannan; Silvia Minardi; David J Ellenbogen; Mitchell J Hallman; Allison C Greene; Jonathan T Yamaguchi; Mark A Plantz; Soyoen Jeong; Kennedy C Sana; Vivek Shah; Chawon Yun; Erin L Hsu; Wellington K Hsu
Journal:  JOR Spine       Date:  2021-12-13

7.  Causes of lower extremity weaknesses after posterior lumbar spine fusion surgery and therapeutic effects of active surgical exploration.

Authors:  Rui Wang; Chunde Li; Xiaodong Yi; Hailin Lu; Yu Wang; Hong Li
Journal:  J Orthop Surg Res       Date:  2020-09-22       Impact factor: 2.359

  7 in total

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