Literature DB >> 2667745

The effect of tamoxifen and estrogen receptor status on survival in gastric carcinoma.

J D Harrison1, D L Morris, I O Ellis, J A Jones, I Jackson.   

Abstract

One hundred patients were entered in a randomized, controlled study of adjuvant tamoxifen therapy in gastric carcinoma. Estrogen receptor status was established by an immunohistologic method (ERD5) and 55.8% of the tumors were positive. Tamoxifen had no overall effect on survival, but there was a significant decrease in the survival time of the patients with ERD5-positive tumors. Estrogen receptor status (by the ERD5 method) is an independent prognostic factor in gastric cancer. Tamoxifen therapy does not prolong survival, and new therapeutic strategies require investigation.

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Year:  1989        PMID： 2667745     DOI： 10.1002/1097-0142(19890901)64:5<1007::aid-cncr2820640506>3.0.co;2-u

Source DB:  PubMed          Journal:  Cancer        ISSN： 0008-543X            Impact factor:   6.860


  20 in total

1.  Expression of ERα36 in gastric cancer samples and their matched normal tissues.

Authors:  Jianjun Wang; Jiajia Li; Rengui Fang; Shuduo Xie; Linbo Wang; Chaoyang Xu
Journal:  Oncol Lett       Date:  2011-10-12       Impact factor: 2.967

2.  Immunological evidence for the identity between the hsp27 estrogen-regulated heat shock protein and the p29 estrogen receptor-associated protein in breast and endometrial cancer.

Authors:  D R Ciocca; E H Luque
Journal:  Breast Cancer Res Treat       Date:  1991-12       Impact factor: 4.872

3.  Differential expression of oestrogen receptor and oestrogen inducible genes in gastric mucosa and cancer.

Authors:  S Singh; R Poulsom; N A Wright; M C Sheppard; M J Langman
Journal:  Gut       Date:  1997-04       Impact factor: 23.059

Review 4.  Diagnosis and treatment of gastric cancer.

Authors:  A Hendlisz; H Bleiberg
Journal:  Drugs       Date:  1995-05       Impact factor: 9.546

5.  Adjuvant FOLFOX-4 in patients with radically resected gastric cancer: Tolerability and prognostic factors.

Authors:  Chiara Carlomagno; Elide Matano; Roberto Bianco; Carolina Cimminiello; Antonella Prudente; Clorindo Pagliarulo; Anna Crispo; Lucia Cannella; Alfonso DE Stefano; Francesco Paolo D'Armiento; Sabino DE Placido
Journal:  Exp Ther Med       Date:  2010-07-01       Impact factor: 2.447

6.  Prognostic role of lemur tyrosine kinase 3 in postoperative gastric cancer.

Authors:  Zhengguang Li; Jun Wu; Mei Ji; Liangrong Shi; Bin Xu; Jingting Jiang; Changping Wu
Journal:  Mol Clin Oncol       Date:  2014-06-03

7.  Sex hormone-receptor-negative tumors have a higher proliferative activity than sex hormone-receptor-positive tumors in human adenocarcinomas of the gastrointestinal tract.

Authors:  D Korenaga; H Orita; T Okuyama; J Kinoshita; S Maekawa; T Ikeda; K Sugimachi
Journal:  Surg Today       Date:  1998       Impact factor: 2.549

8.  The prognosis of patients with gastric cancer possessing sex hormone receptors.

Authors:  M Matsui; O Kojima; S Kawakami; Y Uehara; T Takahashi
Journal:  Surg Today       Date:  1992       Impact factor: 2.549

9.  Diffuse Gastric Cancer During Pregnancy: Report of a Rare Association.

Authors:  Orivaldo Alves Barbosa; Anna Dorotheia Bezerra de Souza; Mayna Raphaela de Carvalho Moura; Elson Jose de Almeida Junior; Joao Paulo Uchoa Fontenele; Fabio de Figuereido Chaves; Jose Walter Correia
Journal:  World J Oncol       Date:  2015-10-26

10.  Oestrogen receptor-alpha contributes to the regulation of the hedgehog signalling pathway in ERalpha-positive gastric cancer.

Authors:  C Kameda; M Nakamura; H Tanaka; A Yamasaki; M Kubo; M Tanaka; H Onishi; M Katano
Journal:  Br J Cancer       Date:  2010-01-19       Impact factor: 7.640
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