Literature DB >> 26677160

Locally advanced adenocarcinoma of the rectum presenting with necrotising fasciitis of the perineum: successful management with early aggressive surgery and multimodal therapy.

Luís Ferreira1, Henrique Alexandrino2, Júlio Soares Leite3, Francisco Castro Sousa3.   

Abstract

Colorectal cancer is a common malignant neoplasm and its treatment usually involves surgery associated, in some cases, depending on the staging, with chemoradiotherapy. Necrotising fasciitis of the perineum is a highly lethal infection of the perineum, perirectal tissues and genitals, requiring emergency surgical debridement, broad-spectrum antibiotics and control of sepsis. We present the case of a 59-year-old man with necrotising fasciitis of the perineum as the first clinical manifestation of locally advanced adenocarcinoma of the rectum, in which successful management consisted of early and aggressive surgical debridement, followed by multimodal therapy with curative intent. 2 years and 6 months after surgery the patient is well, with no evidence of local or systemic relapse. 2015 BMJ Publishing Group Ltd.

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Year:  2015        PMID: 26677160      PMCID: PMC4691936          DOI: 10.1136/bcr-2015-213245

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  15 in total

1.  Rectocutaneous fistula with Fournier's gangrene, a rare presentation of rectal cancer.

Authors:  Simon Rajendran; Ata Khan; Micheal Murphy; Deirdre O'Hanlon
Journal:  BMJ Case Rep       Date:  2011-07-27

Review 2.  Multidisciplinary Management of Locally Advanced Rectal Cancer--An Evolving Landscape?

Authors:  Margaret Lee; Peter Gibbs; Rachel Wong
Journal:  Clin Colorectal Cancer       Date:  2015-06-17       Impact factor: 4.481

3.  CT findings of perforated rectal carcinoma presenting as Fournier's gangrene in the emergency department.

Authors:  Lorraine Ash; Jonathan Hale
Journal:  Emerg Radiol       Date:  2005-06-03

4.  Anal tumor diagnosed after the recovery of Fournier gangrene.

Authors:  Yesim Elgin; Taciser Demirkasimoglu; Bulent Kucukplakci; Muzaffer B Altundag; Kadri Altundag; Cem Misirlioglu; Ergun Sanri; Handan Erkal; Isil Ugur; Pinar Kara; Aytul Ozgen; Nadi Ozdamar
Journal:  Dig Dis Sci       Date:  2006-04-27       Impact factor: 3.199

5.  Rectal diversion without colostomy in Fournier's gangrene.

Authors:  O Estrada; I Martinez; M Del Bas; S Salvans; L A Hidalgo
Journal:  Tech Coloproctol       Date:  2009-05-29       Impact factor: 3.781

Review 6.  Rectal cancer and Fournier's gangrene - current knowledge and therapeutic options.

Authors:  Tomislav Bruketa; Matea Majerovic; Goran Augustin
Journal:  World J Gastroenterol       Date:  2015-08-14       Impact factor: 5.742

7.  Fournier's gangrene: an unusual presentation for rectal carcinoma.

Authors:  R A Gamagami; M Mostafavi; A Gamagami; F Lazorthes
Journal:  Am J Gastroenterol       Date:  1998-04       Impact factor: 10.864

Review 8.  Fournier's gangrene: a review of 1726 cases.

Authors:  N Eke
Journal:  Br J Surg       Date:  2000-06       Impact factor: 6.939

9.  Rectal Cancer, Version 2.2015.

Authors:  Al B Benson; Alan P Venook; Tanios Bekaii-Saab; Emily Chan; Yi-Jen Chen; Harry S Cooper; Paul F Engstrom; Peter C Enzinger; Moon J Fenton; Charles S Fuchs; Jean L Grem; Axel Grothey; Howard S Hochster; Steven Hunt; Ahmed Kamel; Natalie Kirilcuk; Lucille A Leong; Edward Lin; Wells A Messersmith; Mary F Mulcahy; James D Murphy; Steven Nurkin; Eric Rohren; David P Ryan; Leonard Saltz; Sunil Sharma; David Shibata; John M Skibber; Constantinos T Sofocleous; Elena M Stoffel; Eden Stotsky-Himelfarb; Christopher G Willett; Kristina M Gregory; Deborah Freedman-Cass
Journal:  J Natl Compr Canc Netw       Date:  2015-06       Impact factor: 11.908

10.  Rectal cancer presenting as ischio-rectal abscess and Fournier's gangrene--a case report.

Authors:  P J Gupta
Journal:  Eur Rev Med Pharmacol Sci       Date:  2010-02       Impact factor: 3.507

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  2 in total

1.  Bacteraemia due to Parvimonas micra, a commensal pathogen, in a patient with an oesophageal tumour.

Authors:  Rafael García Carretero; Esther Luna-Heredia; Monica Olid-Velilla; Oscar Vazquez-Gomez
Journal:  BMJ Case Rep       Date:  2016-11-18

2.  Not your usual hip pain: necrotising fasciitis secondary to sigmoid perforation.

Authors:  Sarthak Soin; Sumathi Vijaya Rangan; Faisal Shaukat Ali; Chukwudumebi Okafor
Journal:  BMJ Case Rep       Date:  2019-03-14
  2 in total

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