Chrysoula Papastathi1,2, Emmanuel Disse3,4, Julien Berthiller4,5, Martine Laville3,4, Christian Gouillat4,6, Maud Robert4,6. 1. Department of Endocrinology, Diabetology and Nutrition, University Hospital Lyon Sud, Lyon, France. cpapastathi@yahoo.gr. 2. University Claude Bernard Lyon 1, Lyon, France. cpapastathi@yahoo.gr. 3. Department of Endocrinology, Diabetology and Nutrition, University Hospital Lyon Sud, Lyon, France. 4. University Claude Bernard Lyon 1, Lyon, France. 5. Hospices Civils de Lyon, Pôle Information Médicale Evaluation Recherche, Unité d'Epidémiologie Clinique Lyon, Lyon, France. 6. Department of Digestive Surgery, University Hospital Edouard Herriot, Lyon, France.
Abstract
BACKGROUND- OBJECTIVES: Despite pregnancy being a common event following laparoscopic adjustable gastric banding (LAGB), there is little comprehensive data regarding its effect on postoperative outcome. The aim of this study was to assess the impact of pregnancy on the postoperative changes in quality of life (QOL) and total weight loss 3 years after LAGB. SETTING: Multi-institutional, France. METHODS: This is a study of the subgroup of 561 women of childbearing age included in a 3-year prospective multicenter trial assessing the results of patients undergoing LAGB surgery. Data from the 61 women who got pregnant and delivered during the follow-up period were compared with the 270 who did not. RESULTS: Pregnant women achieved lower final weight loss compared to the non-pregnant group [final body mass index (BMI) 35.4 vs. 31.1 kg/m(2), p < 0.0001; excess weight loss (%EBL) 43.6 vs. 64.7 %, p < 0.0001]. Longitudinal assessment demonstrated pregnancy as a significant and independent factor of poor weight loss (p < 0.0001). The timing of conception after LAGB (between the first 18 months or after) had no significant impact on weight loss changes. There was no significant difference in short form-36 health survey (SF-36) QOL scores between both groups. CONCLUSIONS: Pregnancy following gastric banding affects negatively postoperative final weight loss, even if occurring 18 months postoperatively, but has no effect on QOL improvement.
BACKGROUND- OBJECTIVES: Despite pregnancy being a common event following laparoscopic adjustable gastric banding (LAGB), there is little comprehensive data regarding its effect on postoperative outcome. The aim of this study was to assess the impact of pregnancy on the postoperative changes in quality of life (QOL) and total weight loss 3 years after LAGB. SETTING: Multi-institutional, France. METHODS: This is a study of the subgroup of 561 women of childbearing age included in a 3-year prospective multicenter trial assessing the results of patients undergoing LAGB surgery. Data from the 61 women who got pregnant and delivered during the follow-up period were compared with the 270 who did not. RESULTS: Pregnant women achieved lower final weight loss compared to the non-pregnant group [final body mass index (BMI) 35.4 vs. 31.1 kg/m(2), p < 0.0001; excess weight loss (%EBL) 43.6 vs. 64.7 %, p < 0.0001]. Longitudinal assessment demonstrated pregnancy as a significant and independent factor of poor weight loss (p < 0.0001). The timing of conception after LAGB (between the first 18 months or after) had no significant impact on weight loss changes. There was no significant difference in short form-36 health survey (SF-36) QOL scores between both groups. CONCLUSIONS: Pregnancy following gastric banding affects negatively postoperative final weight loss, even if occurring 18 months postoperatively, but has no effect on QOL improvement.
Entities:
Keywords:
Bariatric surgery; Gastric band; Obesity; Pregnancy; Quality of life; Weight loss
Authors: Michael D Lara; Matthew T Baker; Christopher J Larson; Michelle A Mathiason; Pamela J Lambert; Shanu N Kothari Journal: Surg Obes Relat Dis Date: 2005 Jan-Feb Impact factor: 4.734
Authors: Viktoria L Gloy; Matthias Briel; Deepak L Bhatt; Sangeeta R Kashyap; Philip R Schauer; Geltrude Mingrone; Heiner C Bucher; Alain J Nordmann Journal: BMJ Date: 2013-10-22
Authors: Curtis S Harrod; Miriam R Elman; Kimberly K Vesco; Bruce M Wolfe; James E Mitchell; Walter J Pories; Alfons Pomp; Janne Boone-Heinonen; Jonathan Q Purnell Journal: Obesity (Silver Spring) Date: 2020-09-11 Impact factor: 5.002