Literature DB >> 26676039

Rabbit Model for Superantigen-Mediated Lethal Pulmonary Disease.

Kristi L Strandberg1, Jessica H Rotschafer2, Patrick M Schlievert2.   

Abstract

Staphylococcus aureus is a highly significant cause of serious human infections in the USA. Many of these illnesses are mediated by interactions between the host immune system and staphylococcal superantigens (SAgs). Several of these severe staphylococcal infections are initiated in the lungs, making this an important site to study. Here, we describe the rabbit model for investigating the role of staphylococcal SAgs in pulmonary-associated lethal infection and intoxication.

Entities:  

Keywords:  Pulmonary infection; Pulmonary intoxication; Rabbit model; Staphylococcus aureus; Superantigen; Toxic shock syndrome

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Substances:

Year:  2016        PMID: 26676039     DOI: 10.1007/978-1-4939-3344-0_7

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  2 in total

1.  Production of immunodeficient rabbits by multiplex embryo transfer and multiplex gene targeting.

Authors:  Jun Song; Dongshan Yang; Jinxue Ruan; Jifeng Zhang; Yuqing Eugene Chen; Jie Xu
Journal:  Sci Rep       Date:  2017-09-22       Impact factor: 4.379

2.  Bacterial and Pneumocystis Infections in the Lungs of Gene-Knockout Rabbits with Severe Combined Immunodeficiency.

Authors:  Jun Song; Guoshun Wang; Mark J Hoenerhoff; Jinxue Ruan; Dongshan Yang; Jifeng Zhang; Jibing Yang; Patrick A Lester; Robert Sigler; Michael Bradley; Samantha Eckley; Kelsey Cornelius; Kong Chen; Jay K Kolls; Li Peng; Liang Ma; Yuqing Eugene Chen; Fei Sun; Jie Xu
Journal:  Front Immunol       Date:  2018-03-09       Impact factor: 7.561

  2 in total

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