Literature DB >> 26675333

Human NUP98-IQCG fusion protein induces acute myelomonocytic leukemia in mice by dysregulating the Hox/Pbx3 pathway.

M M Pan1, Q Y Zhang1,2, Y Y Wang1, P Liu1, R B Ren1, J Y Huang1, L T Chen1, X D Xi1, Z Chen1,2, S J Chen1,2.   

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Year:  2015        PMID： 26675333     DOI： 10.1038/leu.2015.347

Source DB:  PubMed          Journal:  Leukemia        ISSN： 0887-6924            Impact factor:   11.528


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  14 in total

1.  Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b.

Authors:  E Kroon; J Krosl; U Thorsteinsdottir; S Baban; A M Buchberg; G Sauvageau
Journal:  EMBO J       Date:  1998-07-01       Impact factor: 11.598

2.  A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression.

Authors:  Kevin C Wang; Yul W Yang; Bo Liu; Amartya Sanyal; Ryan Corces-Zimmerman; Yong Chen; Bryan R Lajoie; Angeline Protacio; Ryan A Flynn; Rajnish A Gupta; Joanna Wysocka; Ming Lei; Job Dekker; Jill A Helms; Howard Y Chang
Journal:  Nature       Date:  2011-03-20       Impact factor: 49.962

3.  Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Authors:  Aravind Subramanian; Pablo Tamayo; Vamsi K Mootha; Sayan Mukherjee; Benjamin L Ebert; Michael A Gillette; Amanda Paulovich; Scott L Pomeroy; Todd R Golub; Eric S Lander; Jill P Mesirov
Journal:  Proc Natl Acad Sci U S A       Date:  2005-09-30       Impact factor: 11.205

4.  Defining roles for HOX and MEIS1 genes in induction of acute myeloid leukemia.

Authors:  U Thorsteinsdottir; E Kroon; L Jerome; F Blasi; G Sauvageau
Journal:  Mol Cell Biol       Date:  2001-01       Impact factor: 4.272

5.  HOXB6 overexpression in murine bone marrow immortalizes a myelomonocytic precursor in vitro and causes hematopoietic stem cell expansion and acute myeloid leukemia in vivo.

Authors:  Neal A Fischbach; Sofia Rozenfeld; Weifang Shen; Stephen Fong; Daniel Chrobak; David Ginzinger; Scott C Kogan; Archana Radhakrishnan; Michelle M Le Beau; Corey Largman; H Jeffrey Lawrence
Journal:  Blood       Date:  2004-11-02       Impact factor: 22.113

6.  Induction of acute myeloid leukemia in mice by the human leukemia-specific fusion gene NUP98-HOXD13 in concert with Meis1.

Authors:  Nicolas Pineault; Christian Buske; Michaela Feuring-Buske; Carolina Abramovich; Patty Rosten; Donna E Hogge; Peter D Aplan; R Keith Humphries
Journal:  Blood       Date:  2003-01-23       Impact factor: 22.113

7.  AML1 mutations induced MDS and MDS/AML in a mouse BMT model.

Authors:  Naoko Watanabe-Okochi; Jiro Kitaura; Ryoichi Ono; Hironori Harada; Yuka Harada; Yukiko Komeno; Hideaki Nakajima; Tetsuya Nosaka; Toshiya Inaba; Toshio Kitamura
Journal:  Blood       Date:  2008-01-11       Impact factor: 22.113

8.  PBX3 is an important cofactor of HOXA9 in leukemogenesis.

Authors:  Zejuan Li; Zhiyu Zhang; Yuanyuan Li; Stephen Arnovitz; Ping Chen; Hao Huang; Xi Jiang; Gia-Ming Hong; Rejani B Kunjamma; Haomin Ren; Chunjiang He; Chong-Zhi Wang; Abdel G Elkahloun; Peter J M Valk; Konstanze Döhner; Mary Beth Neilly; Lars Bullinger; Ruud Delwel; Bob Löwenberg; Paul P Liu; Richard Morgan; Janet D Rowley; Chun-Su Yuan; Jianjun Chen
Journal:  Blood       Date:  2012-12-20       Impact factor: 22.113

9.  Coordinated expression of ncRNAs and HOX mRNAs in the human HOXA locus.

Authors:  Yasnory T F Sasaki; Miho Sano; Taishin Kin; Kiyoshi Asai; Tetsuro Hirose
Journal:  Biochem Biophys Res Commun       Date:  2007-04-09       Impact factor: 3.575

10.  A new fusion gene NUP98-IQCG identified in an acute T-lymphoid/myeloid leukemia with a t(3;11)(q29q13;p15)del(3)(q29) translocation.

Authors:  Q Pan; Y-J Zhu; B-W Gu; X Cai; X-T Bai; H-Y Yun; J Zhu; B Chen; L Weng; Z Chen; Y-Q Xue; S-J Chen
Journal:  Oncogene       Date:  2007-12-17       Impact factor: 9.867
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  3 in total

1.  Inhibition of the nuclear export of p65 and IQCG in leukemogenesis by NUP98-IQCG.

Authors:  Mengmeng Pan; Qiyao Zhang; Ping Liu; Jinyan Huang; Yueying Wang; Saijuan Chen
Journal:  Front Med       Date:  2016-12-23       Impact factor: 4.592

Review 2.  Mechanistic insights and potential therapeutic approaches for NUP98-rearranged hematologic malignancies.

Authors:  Nicole L Michmerhuizen; Jeffery M Klco; Charles G Mullighan
Journal:  Blood       Date:  2020-11-12       Impact factor: 22.113

3.  P2X7 promotes the progression of MLL-AF9 induced acute myeloid leukemia by upregulation of Pbx3.

Authors:  Wenli Feng; Xiao Yang; Lina Wang; Rong Wang; Feifei Yang; Hao Wang; Xiaoli Liu; Qian Ren; Yingchi Zhang; Xiaofan Zhu; Guoguang Zheng
Journal:  Haematologica       Date:  2021-05-01       Impact factor: 9.941
  3 in total

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