Literature DB >> 26673857

Comparative Evaluation of Propolis, Metronidazole with Chlorhexidine, Calcium Hydroxide and Curcuma Longa Extract as Intracanal Medicament Against E.faecalis- An Invitro Study.

Shruti Saha1, Rashmi Nair2, Hemant Asrani3.   

Abstract

INTRODUCTION: The increase of potential side effects and safety concerns of conventional medicaments have led to the recent popularity of herbal alternative medications. The herbal products are known for its high antimicrobial activity, biocompatibility, anti-inflammatory and antioxidant properties. AIM: The purpose of this study was to investigate and compare the effectiveness of Propolis, Metronidazole with Chlorhexidine gel, Curcuma Longa and Calcium Hydroxide for elimination of E.faecalis bacteria in extracted teeth samples.
MATERIALS AND METHODS: Ninety extracted single rooted intact teeth were taken for the study. Decoronation, removal of apices and chemomechanical preparation was done for all samples. These sterilized samples were then contaminated with pure culture of E.faecalis under laminar flow. The samples were incubated for a period of 21 days. The infected samples were assigned to 5 groups: Group I- Propolis; Group II- Metronidazole with Chlorhexidine gel; Group III- Calcium hydroxide; Group IV- Curcuma Longa; and control group- Saline. Efficacy of newer intracanal medicaments against E.faecalis were carried out in the samples at the end of 1, 2 & 5 days for each group with the help of colorimeter. Student paired t-test, ANOVA and multiple tukey test were used for statistical analysis.
RESULTS: The value of optical density was statistically significant in all groups when compared to that of control group. Group I (Propolis) produced better antimicrobial efficacy followed by Chlorhexidine Metronidazole combination, Curcuma Longa and Calcium hydroxide.
CONCLUSION: Within the limitations of this study, it can be concluded that Propolis showed better antimicrobial properties against E.faecalis than other medicaments.

Entities:  

Keywords:  Antimicrobial efficacy; Endodontic treatment; Periradicular diseases

Year:  2015        PMID: 26673857      PMCID: PMC4668516          DOI: 10.7860/JCDR/2015/14093.6734

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  21 in total

1.  Microbiological status of root-filled teeth with apical periodontitis.

Authors:  A Molander; C Reit; G Dahlén; T Kvist
Journal:  Int Endod J       Date:  1998-01       Impact factor: 5.264

2.  Antimicrobial action of propolis and some of its components: the effects on growth, membrane potential and motility of bacteria.

Authors:  O K Mirzoeva; R N Grishanin; P C Calder
Journal:  Microbiol Res       Date:  1997-09       Impact factor: 5.415

3.  Effectiveness of 2% chlorhexidine gel and calcium hydroxide against Enterococcus faecalis in bovine root dentine in vitro.

Authors:  B P F A Gomes; S F C Souza; C C R Ferraz; F B Teixeira; A A Zaia; L Valdrighi; F J Souza-Filho
Journal:  Int Endod J       Date:  2003-04       Impact factor: 5.264

Review 4.  Enterococcus faecalis: its role in root canal treatment failure and current concepts in retreatment.

Authors:  Charles H Stuart; Scott A Schwartz; Thomas J Beeson; Christopher B Owatz
Journal:  J Endod       Date:  2006-02       Impact factor: 4.171

5.  Comparative evaluation of propolis and triantibiotic mixture as an intracanal medicament against Enterococcus faecalis.

Authors:  Manavalan Madhana Madhubala; Narasimhan Srinivasan; Shafie Ahamed
Journal:  J Endod       Date:  2011-07-16       Impact factor: 4.171

6.  Chlorhexidine as a root canal medicament for treating inflammatory lesions in the periodontal space.

Authors:  S Lindskog; A M Pierce; L Blomlöf
Journal:  Endod Dent Traumatol       Date:  1998-08

7.  Effectiveness of propolis and calcium hydroxide as a short-term intracanal medicament against Enterococcus faecalis: a laboratory study.

Authors:  Lama Awawdeh; Maha Al-Beitawi; Mohammad Hammad
Journal:  Aust Endod J       Date:  2009-08       Impact factor: 1.659

8.  Antimicrobial efficacy of a polymeric chlorhexidine release device using in vitro model of Enterococcus faecalis dentinal tubule infection.

Authors:  Yoon Lee; Seung Hyun Han; Sang-Hee Hong; Jin-Kyung Lee; Hye Ji; Kee-Yeon Kum
Journal:  J Endod       Date:  2008-05-22       Impact factor: 4.171

9.  Disinfection of dentinal tubules with 2% chlorhexidine, 2% metronidazole, bioactive glass when compared with calcium hydroxide as intracanal medicaments.

Authors:  Jogikalmat Krithikadatta; Rajamani Indira; Alfred Leo Dorothykalyani
Journal:  J Endod       Date:  2007-12       Impact factor: 4.171

10.  Removal efficiency of propolis paste dressing from the root canal.

Authors:  Fausto Rodrigo Victorino; Clovis Monteiro Bramante; Ronald Ordinola Zapata; Ana Regina Casaroto; Roberto Brandão Garcia; Ivaldo Gomes de Moraes; Mirian Marubayashi Hidalgo
Journal:  J Appl Oral Sci       Date:  2010-12       Impact factor: 2.698

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  3 in total

1.  Effects of photodynamic therapy, 2 % chlorhexidine, triantibiotic mixture, propolis and ozone on root canals experimentally infected with Enterococcus faecalis: an in vitro study.

Authors:  Fabio Camacho-Alonso; P Salmerón-Lozano; Y Martínez-Beneyto
Journal:  Odontology       Date:  2016-10-22       Impact factor: 2.634

2.  The comparison of calcium hydroxide, curcumin, and Aloe vera antibacterial effects on 6-week-old Enterococcus faecalis biofilm as an intracanal medicament: An in vitro study.

Authors:  Mahsa Eskandarinezhad; Mohammad Hossein Soroush Barhaghi; Kimia Allameh; Amirhouman Sadrhaghighi; Katayoun Katebi
Journal:  Dent Res J (Isfahan)       Date:  2022-02-28

3.  Comparative evaluation of antimicrobial effect of herbal root canal irrigants (Morinda citrifolia, Azadirachta indica, Aloe vera) with sodium hypochlorite: An in vitro study.

Authors:  Prashant Babaji; Kiran Jagtap; Himani Lau; Nandita Bansal; S Thajuraj; Priti Sondhi
Journal:  J Int Soc Prev Community Dent       Date:  2016-05-30
  3 in total

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