Literature DB >> 26673786

CD248/Endosialin: A Novel Pericyte Target in Renal Fibrosis.

Monica Chang-Panesso, Benjamin D Humphreys.   

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Year:  2015        PMID: 26673786      PMCID: PMC4725584          DOI: 10.1159/000440890

Source DB:  PubMed          Journal:  Nephron        ISSN: 1660-8151            Impact factor:   2.847


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  14 in total

1.  A first-in-human phase I study of MORAb-004, a monoclonal antibody to endosialin in patients with advanced solid tumors.

Authors:  Luis A Diaz; Christina M Coughlin; Susan C Weil; Jean Fishel; Mrinal M Gounder; Susan Lawrence; Nilofer Azad; Daniel J O'Shannessy; Luigi Grasso; Jason Wustner; Wolfgang Ebel; Richard D Carvajal
Journal:  Clin Cancer Res       Date:  2014-11-14       Impact factor: 12.531

2.  Intrinsic epithelial cells repair the kidney after injury.

Authors:  Benjamin D Humphreys; M Todd Valerius; Akio Kobayashi; Joshua W Mugford; Savuth Soeung; Jeremy S Duffield; Andrew P McMahon; Joseph V Bonventre
Journal:  Cell Stem Cell       Date:  2008-03-06       Impact factor: 24.633

Review 3.  Understanding the origin, activation and regulation of matrix-producing myofibroblasts for treatment of fibrotic disease.

Authors:  Rafael Kramann; Derek P DiRocco; Benjamin D Humphreys
Journal:  J Pathol       Date:  2013-11       Impact factor: 7.996

4.  Anti-Endosialin Antibody-Drug Conjugate: Potential in Sarcoma and Other Malignancies.

Authors:  Cecile Rouleau; Diego A Gianolio; Robert Smale; Stephanie D Roth; Roy Krumbholz; Jay Harper; Kenneth J Munroe; Tessa L Green; Bruce C Horten; Steven M Schmid; Beverly A Teicher
Journal:  Mol Cancer Ther       Date:  2015-07-16       Impact factor: 6.261

5.  Paracrine Wnt1 Drives Interstitial Fibrosis without Inflammation by Tubulointerstitial Cross-Talk.

Authors:  Omar H Maarouf; Anusha Aravamudhan; Deepika Rangarajan; Tetsuro Kusaba; Victor Zhang; Jeremy Welborn; Daniel Gauvin; Xiuyun Hou; Rafael Kramann; Benjamin D Humphreys
Journal:  J Am Soc Nephrol       Date:  2015-07-23       Impact factor: 10.121

6.  Identification of endosialin, a cell surface glycoprotein of vascular endothelial cells in human cancer.

Authors:  W J Rettig; P Garin-Chesa; J H Healey; S L Su; E A Jaffe; L J Old
Journal:  Proc Natl Acad Sci U S A       Date:  1992-11-15       Impact factor: 11.205

Review 7.  PDGF and the progression of renal disease.

Authors:  Peter Boor; Tammo Ostendorf; Jürgen Floege
Journal:  Nephrol Dial Transplant       Date:  2014-02       Impact factor: 5.992

8.  A phase 3 trial of pirfenidone in patients with idiopathic pulmonary fibrosis.

Authors:  Talmadge E King; Williamson Z Bradford; Socorro Castro-Bernardini; Elizabeth A Fagan; Ian Glaspole; Marilyn K Glassberg; Eduard Gorina; Peter M Hopkins; David Kardatzke; Lisa Lancaster; David J Lederer; Steven D Nathan; Carlos A Pereira; Steven A Sahn; Robert Sussman; Jeffrey J Swigris; Paul W Noble
Journal:  N Engl J Med       Date:  2014-05-18       Impact factor: 91.245

9.  Efficacy and safety of nintedanib in idiopathic pulmonary fibrosis.

Authors:  Luca Richeldi; Roland M du Bois; Ganesh Raghu; Arata Azuma; Kevin K Brown; Ulrich Costabel; Vincent Cottin; Kevin R Flaherty; David M Hansell; Yoshikazu Inoue; Dong Soon Kim; Martin Kolb; Andrew G Nicholson; Paul W Noble; Moisés Selman; Hiroyuki Taniguchi; Michèle Brun; Florence Le Maulf; Mannaïg Girard; Susanne Stowasser; Rozsa Schlenker-Herceg; Bernd Disse; Harold R Collard
Journal:  N Engl J Med       Date:  2014-05-18       Impact factor: 91.245

10.  CD248/endosialin critically regulates hepatic stellate cell proliferation during chronic liver injury via a PDGF-regulated mechanism.

Authors:  Annika Wilhelm; Victoria Aldridge; Debashis Haldar; Amy J Naylor; Christopher J Weston; Ditte Hedegaard; Abhilok Garg; Janine Fear; Gary M Reynolds; Adam P Croft; Neil C Henderson; Christopher D Buckley; Philip N Newsome
Journal:  Gut       Date:  2015-06-15       Impact factor: 23.059

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  5 in total

1.  Hepatic stellate cells limit hepatocellular carcinoma progression through the orphan receptor endosialin.

Authors:  Carolin Mogler; Courtney König; Matthias Wieland; Anja Runge; Eva Besemfelder; Dorde Komljenovic; Thomas Longerich; Peter Schirmacher; Hellmut G Augustin
Journal:  EMBO Mol Med       Date:  2017-06       Impact factor: 12.137

Review 2.  CD248: A therapeutic target in cancer and fibrotic diseases.

Authors:  Beverly A Teicher
Journal:  Oncotarget       Date:  2019-01-29

3.  Adventitial Cell Atlas of wt (Wild Type) and ApoE (Apolipoprotein E)-Deficient Mice Defined by Single-Cell RNA Sequencing.

Authors:  Wenduo Gu; Zhichao Ni; Yuan-Qing Tan; Jiacheng Deng; Si-Jin Zhang; Zi-Chao Lv; Xiao-Jian Wang; Ting Chen; Zhongyi Zhang; Yanhua Hu; Zhi-Cheng Jing; Qingbo Xu
Journal:  Arterioscler Thromb Vasc Biol       Date:  2019-06       Impact factor: 8.311

Review 4.  C-type lectin domain group 14 proteins in vascular biology, cancer and inflammation.

Authors:  Kabir A Khan; Jack L McMurray; Fiyaz Mohammed; Roy Bicknell
Journal:  FEBS J       Date:  2019-07-29       Impact factor: 5.542

5.  Blocking CD248 molecules in perivascular stromal cells of patients with systemic sclerosis strongly inhibits their differentiation toward myofibroblasts and proliferation: a new potential target for antifibrotic therapy.

Authors:  Paola Di Benedetto; Vasiliki Liakouli; Piero Ruscitti; Onorina Berardicurti; Francesco Carubbi; Noemi Panzera; Salvatore Di Bartolomeo; Giuliana Guggino; Francesco Ciccia; Giovanni Triolo; Paola Cipriani; Roberto Giacomelli
Journal:  Arthritis Res Ther       Date:  2018-10-03       Impact factor: 5.156

  5 in total

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